Essays about: "drug development"

Showing result 1 - 5 of 277 essays containing the words drug development.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  3. 2. Combining Cell Painting, Gene Expression and Structure-Activity Data for Mechanism of Action Prediction

    University essay from Uppsala universitet/Nationellt resurscentrum för biologi och bioteknik

    Author : Erik Everett Palm; [2023]
    Keywords : bioinformatics; deep learning; machine learning; joint model; tabular data; image data;

    Abstract : The rapid progress in high-throughput omics methods and high-resolution morphological profiling, coupled with the significant advances in machine learning (ML) and deep learning (DL), has opened new avenues for tackling the notoriously difficult problem of predicting the Mechanism of Action (MoA) for a drug of clinical interest. Understanding a drug's MoA can enrich our knowledge of its biological activity, shed light on potential side effects, and serve as a predictor of clinical success. READ MORE

  4. 3. Advancements of 3D Bioprinting : A market development study

    University essay from Uppsala universitet/Institutionen för samhällsbyggnad och industriell teknik

    Author : Alexander Brandt; [2023]
    Keywords : 3D bioprinting; Market; market developmet; Technology readiness levels;

    Abstract : In most cases new technology emergence does not guarantee overnight success nor is it developed overnight, rather it is a result of industry expertise spanning over several fields of research. 3D bioprinting is an industry that promises revolutionary implications for healthcare and scholars are discussing application areas such as tissue for oncology research, tissue for patient specific drug development and lastly complex organs for implantation. READ MORE

  5. 4. Paying the Piper : The Consequences of Including Generic Prices in Reimbursement Decisions for Prescription Pharmaceuticals

    University essay from Linköpings universitet/Nationalekonomi; Linköpings universitet/Filosofiska fakulteten

    Author : Anton Klockhoff; Wilmer Larsson; [2023]
    Keywords : pharmaceutical reimbursement; genericization; endogenous pricing; treatment displacement; cost-effectiveness analysis; R D incentives;

    Abstract : Objectives: The Dental and Pharmaceutical Benefits Agency (TLV) is responsible for deciding which prescription pharmaceuticals should be subsidized in Sweden. Cost-effectiveness analyses are fundamental to its decision-making, but future price reductions following patent expiry are excluded from these analyses. READ MORE

  6. 5. Land Inequality, Agrarian Development and Peace in Colombia : A Political Ecology View

    University essay from KTH/Hållbar utveckling, miljövetenskap och teknik

    Author : Michelle Silva Vásquez; [2023]
    Keywords : Colombia; land accumulation; dispossession; peace; political ecology; peasants;

    Abstract : One of the major problems that characterizes the Colombian countryside is the extreme concentration of land. When addressing the question of how land has been concentrated in Colombia, often the emphasis is placed on phenomena such as armed violence and drug-trafficking. READ MORE