Essays about: "drug formulation"
Showing result 1 - 5 of 34 essays containing the words drug formulation.
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1. Exploring alternative surfactants to replace PEG within lipid nanoparticles
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE
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2. DRY POWDER FOR INHALATION - INFLUENCE OF MIXING PROCESS AND ADDITION OF MAGNESIUM STEARATE
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : For efficient treatment of many diseases of the lung, it is beneficial to deliver the medicine to the respiratory tract directly. This ensures a rapid response since it can enter the bloodstream directly through the alveolar epithelium. Consequently, also decreases systemic effects due to the local treatment. READ MORE
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3. Methods to study device induced aggregation of proteins
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : This work developed a method for the investigation of how medical devices, such as syringes and needles, affect the formation of subvisible particles in a protein drug without excipients. Protein-based pharmaceuticals are well known to be sensitive to different kinds of stress, and exposure to stress during the use of this device is unavoidable. READ MORE
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4. The Potential Use of Degradable Starch Microspheres as a Carrier for Nasal Drug Administration
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Intranasal drug delivery is a practical and accessible method for treating localized symptoms as well as achieving systemic drug absorption. The approach takes advantage of the permeability, vascularization, and limited enzymatic activity of nasal tissue, leading to enhanced drug absorption. READ MORE
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5. The effect of lactose fines, magnesium stearate, choice of mixer and mixing process on the performance of adhesive mixtures for inhalation
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Dry powder inhaler (DPI) formulation is a major area of interest since they are employed by the healthcare system to treat relevant chronic diseases like asthma. Previous research has established that the manufacturing process and formulation composition are key for the active pharmaceutical ingredient to reach the lungs and achieve therapeutic effects. READ MORE
