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Showing result 1 - 5 of 35 essays matching the above criteria.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  3. 2. The Effect of Alternative Tungsten Carbide Grain Size Distribution on Microstructure and Mechanical Properties in Cemented Carbides

    University essay from KTH/Materialvetenskap

    Author : Filip Ivarsson; [2022]
    Keywords : Cemented Carbides; WC Grain Size Distribution; Mechanical Properties; Microstructure Analysis; Hårdmetall; WC Kornstorleksfördelning; Mekaniska Egenskaper; Mikrostruktur Analys;

    Abstract : In the constant pursuit of better-performing cemented carbides, recent studies suggest that a combination of better hardness and toughness can be obtained by changing its WC grain size distribution. As the area is still rather unexplored, this  thesis  aims  to  broaden  the  knowledge  and  answer  whether mechanical properties can be changed by changing the WC grain size distribution, in the context of mining drill bit inserts. READ MORE

  4. 3. Exploring Column Update Elimination Optimization for Spike-Timing-Dependent Plasticity Learning Rule

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Ojasvi Singh; [2022]
    Keywords : Spike-Timing Dependent Plasticity; neuromorphic computing; Hebbian Learning; Spiking Neural Networks; memory optimization.; Spike-Timing Beroende Plasticitet; neuromorfisk beräkning; Hebbiansk inlärning; Spiking Neural Networks; Minnes optimering;

    Abstract : Hebbian learning based neural network learning rules when implemented on hardware, store their synaptic weights in the form of a two-dimensional matrix. The storage of synaptic weights demands large memory bandwidth and storage. READ MORE

  5. 4. Antenna Design and Link Performance Verification of Antennas for 5G mmWave Handheld Devices

    University essay from Lunds universitet/Institutionen för elektro- och informationsteknik

    Author : Vinodhini Mylai Chandrasekaran; Nikhila Chinnayanapalli Ravi; [2022]
    Keywords : Antenna Design; mmWave frequency; 5G; FEKO; Technology and Engineering;

    Abstract : The purpose of the thesis is to design a new antenna system and to verify its link performance in 5G FR2 mmWave frequency for handheld devices to enable cellular communication. The main objective is to design an antenna primarily at 28GHz and 39GHz to enhance spectrum efficiency, along with improved transmission data rates, enabling new cases like Augmented Reality (AR), Virtual Reality (VR) and many more such applications. READ MORE

  6. 5. Effect of Touch on Cotton and Maize : influence on plant morphology and feeding preference in Spodoptera littoralis

    University essay from SLU/Dept. of Plant Protection Biology

    Author : Anna Magnusson; [2022]
    Keywords : Mechanical stimuli; cotton; maize; thigmomorphogenesis; Spodoptera littoralis; induced defence; plant-plant interaction;

    Abstract : Plants are constantly exposed to touch and mechanical stimuli in natural environments, from rain, wind, animals and plant neighbours. However, current knowledge and understanding of how touch physiologically affects plants are limited. READ MORE