Essays about: "dual pathways"

Showing result 1 - 5 of 8 essays containing the words dual pathways.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  3. 2. Investigating ERβ chromatin binding and its potential interaction with LRH-1 in an ovarian context

    University essay from KTH/Proteinvetenskap

    Author : Mick Phenphak; [2023]
    Keywords : estrogen receptor beta; ovary; granulosa cells; ChIP; qPCR; östrogen receptor beta; äggstock; granulosa celler; ChIP; qPCR;

    Abstract : Invasiv äggstockscancer anses vara en av de mest dödligaste gynekologiska maligniteterna. Granulosacelltumör i äggstocken är en sällsynt subtyp av äggstockstumör, som utgör 1–5% av alla äggstockstumörer. De kan kännetecknas av den långsamma tillväxthastigheten och produktionen av höga östrogennivåer. READ MORE

  4. 3. “I am the problem, it’s me” : A Netnographic Analysis of ‘Swiftie’ Prosumers on YouTube Shorts

    University essay from Malmö universitet/Institutionen för konst, kultur och kommunikation (K3)

    Author : Írisz Beatrix Ősze; [2023]
    Keywords : Fan Studies; music fandom; online fan communities; Swifties U G; prosumption; interpretivism; Netnography; YouTube Shorts;

    Abstract : The popularity of Taylor Swift has been growing rapidly on social media after the release of her ‘Midnights’ album on 21 October 2022. The lead single of the album, ‘Anti- Hero’ and the ‘Anti-Hero Challenge’ initiated by the singer inspired 17 thousand fans (Swifties) to share their own anti-heroic stories inspired by the song. READ MORE

  5. 4. Stereoselective synthesis of unnatural α-amino acids through photoredox catalyzed C–H activation

    University essay from KTH/Kemi

    Author : Ludwig Wåhlin; [2021]
    Keywords : photoredox catalysis; C–H functionalization; hydrogen atom transfer; unnatural amino acids; radicals; fotoredoxkatalys; C–H-funktionalisering; väteatomsöverföring; icke-naturliga aminosyror; radikaler;

    Abstract : Fotoredoxkatalys har nyligen genomgått en renässans inom organisk kemi då metoden har möjliggjort framtagandet utav nya reaktionsvägar med milda reaktionsbetingelser genom att använda sig av synligt ljus. I det här arbetet undersöktes metodens bredd genom att kombinera metoden med väteatomöverföringskatalys för att funktionalisera C–H bindningar i α-position till heteroatomer och på så sätt skapa icke-naturliga α-aminosyror. READ MORE

  6. 5. The evaluation of preparation techniques for the measurements of hydrogen isotope ratios in ecology

    University essay from Umeå universitet/Institutionen för ekologi, miljö och geovetenskap

    Author : Kusal Weragama; [2021]
    Keywords : Deuterium; liquid water equilibration; steam equilibration; exchangeable H fraction; non-exchangeable H; Equilibrium fractionation factor; Isotopic soil fraction;

    Abstract : The stable isotope ratio of non-exchangeable hydrogen (δ2Hn) emerged as a promising new tool for source attribution in aquatic ecology, which can better discriminate between the organic matter sources. However, determining the absolute isotopic values is problematic due to the functional groups with hydrogen (H) that can easily exchange with the ambient water. READ MORE