Essays about: "endothelial"

Showing result 1 - 5 of 54 essays containing the word endothelial.

1. 1. Development and testing of in-house automatized spatial omics data analysis tool : NIPMAP (Niche-Phenotype Mapping)

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Raziyeh Mohseni; [2023]
   Keywords : ;

   Abstract : The functional and anatomical characteristics of cancer cells vary among patients. Additionally, therapeutic approaches display varying responses in different individuals and cancer types due to the anatomical and functional complexity of tumor. READ MORE

3. 2. The Effects of Periodontal Treatment on Atherosclerosis : A Systematic Review

   University essay from Malmö universitet/Odontologiska fakulteten (OD)

   Author : Ifrah Ahmed; [2023]
   Keywords : Atherosclerosis; Atherosclerotic cardiovascular disease; Cardiovascular disease; Periodontal disease; Periodontitis;

   Abstract : Aim: The aim of the study was to systematically review the evidence from clinical intervention trials evaluating the effect of periodontal treatment (PT) on surrogate markers on individuals diagnosed with periodontal disease (PD) and atherosclerotic cardiovascular disease (ACVD). The systematic review was based on quantitative literature. READ MORE

4. 3. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Jonathan Efverström; [2023]
   Keywords : Blood-brain barrier; In-Cell BBB-trans assay; mTfR1; Transferrin receptor; scFc-scFv8D3; Blod-hjärn barriären; mTfR1; Transferrin receptorn; scFc-scFv8D3;

   Abstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE

5. 4. Molecular characterization of vascular malformations using single-cell RNA sequencing and immunohistological analysis

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Amanda Norrén; [2023]
   Keywords : ;

   Abstract : CCM is a human disease in which vascular malformations develop in the central nervous system, predominantly in the brain. The malformations which can measure up to several centimeters in size are dilated and leaky vessels, with unstable cellular junctions and thin vessel walls. READ MORE

6. 5. Testing Coagulation Potential of Extracellular Vesicles Derived from Aortic Stenosis Patients on Human Cardiac Spheroids

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Muhammad Nafiz Ikhwan Bin Nor Fuad; [2023]
   Keywords : Extracellular vesicles; human aortic endothelial cells; tissue factor; TNFα; coagulation pathway; cardiac spheroids;

   Abstract : Cardiovascular diseases have always been the leading cause of global morbidity and mortality. Aortic stenosis, which is a kind of cardiovascular disease has a high prevalence in elderlies that are 75 years and older. Currently, the only available treatment would be valve replacement surgery. READ MORE