Essays about: "enhancer elements"

Showing result 1 - 5 of 7 essays containing the words enhancer elements.

  1. 1. Systematic comparison of gene regulatory datasets using experimentally validated enhancers

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Xue Dong; [2020]
    Keywords : Capture Hi-C; ChIP-seq; enhancer; promoter-enhancer interactions; eQTLs;

    Abstract : Promoter-enhancer interactions are essential for gene regulating, Capture Hi-C is a chromosome conformation capture method to map promoter-enhancer interactions at high resolution. We have Capture Hi-C data forGM12878 cells, immortalized primary B lymphocytes, in three replicates. READ MORE

  3. 2. A zebrafish-based system to study the impact of environmental factors in Inflammatory Bowel Disease (IBD)

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Mikaela Westling; [2020]
    Keywords : IBD; non-coding regions; zebrafish; in vivo; transgenic dual reporters; enhancer activity; polyfluoroalkyl substances; dietary sensors;

    Abstract : Inflammatory Bowel Disease (IBD) is a chronic disorder that affects millions of peopleworldwide. Although the etiology behind the disease is yet unknown, current theoriespropose a complex interplay between genetic susceptibility, exposure to environmentalfactors and exacerbated immune responses. READ MORE

  4. 3. Characterisation of Transcription Factor Regulation During the Development of Zebrafish Craniofacial Structures

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Jake Leyhr; [2018]
    Keywords : ;

    Abstract : The appearance of jaws approximately 420 million years ago was a major event in vertebrate evolution. This new structure allowed gnathostomes to take on roles as active predators and increase their energy intake, facilitating their success as a group. READ MORE

  5. 4. Immersive and Transcendent Experiences in Underground Clubs: Theorizing the Role of the Elements that Shape the Immersive Experience

    University essay from Göteborgs universitet/Graduate School

    Author : Anita Rafiei; [2016-09-22]
    Keywords : immersion; transcendent experience; extraordinary experience; underground club;

    Abstract : This study explores and theorizes the roles of the elements that shape immersive and transcendent experiences in underground clubs. Based on phenomenology inspired interviews the findings show how the immersive and transcendent experiences are marked by both social and introvert aspects. READ MORE

  6. 5. Alternative splicing and its regulation under normal and abnormal conditions

    University essay from Institutionen för fysik, kemi och biologi

    Author : Jenny Ackelman; [2010]
    Keywords : Alternative splicing; ESE; ESS; hnRNP proteins; ISE; ISS; Regulation; Spliceosome; SR proteins;

    Abstract : During the maturation of pre-mRNA introns are removed and exons are spliced together, to form a primary transcript, a reaction that is catalyzed by the spliceosome. Alternative splicing is a complex reaction that mainly utilizes one of four mechanisms; exon skipping, 5’ splice site choice, 3’ splice site choice and intron retention. READ MORE