Essays about: "example of conclusion of drug"

Showing result 1 - 5 of 12 essays containing the words example of conclusion of drug.

  1. 1. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sara Forsberg; [2023]
    Keywords : High-throughput analysis; Impurity profiling; UHPLC-HRMS; Peptide characterization; Peptide descriptors; Analytical chemistry; Technology and Engineering;

    Abstract : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. READ MORE

  3. 2. Structural and Functional Characterisation of the Human Mitochondrial Pyruvate Carrier

    University essay from Lunds universitet/Kemiska institutionen

    Author : Simon Gripvall; [2023]
    Keywords : biochemistry; complex; MPC; proteoliposomes; pyruvate; transport; Chemistry;

    Abstract : The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases. READ MORE

  4. 3. Risk Communication of New Drugs : A qualitative interview study

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Märta Lindquist; [2022]
    Keywords : ;

    Abstract : Background: Pharmaceutical development has taken new ground in recent decades and placed new demands on the regulations. Since 2005, a risk management plan (RMP) has been required when applying for a first marketing authorization for a drug. The RMP forms the basis for how identified risks with the drug are to be managed. READ MORE

  5. 4. Development of a reporter gene assay on an automated platform

    University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Author : Fanny Redin; [2021]
    Keywords : Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

    Abstract : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. READ MORE

  6. 5. The art of making a comprehensive stability study

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Roman Lord; [2020]
    Keywords : Biopharmaceuticals; mAbs; SEC; stability study design; technical analytical chemistry; teknisk analytisk kemi; Technology and Engineering; Chemistry;

    Abstract : There is a need for harmonisation of stability study designs of monoclonal antibodies. Monoclonal antibodies (mAbs) are widely used in treatments for various diseases. Like all drugs, their quality must be verified through stability studies. READ MORE