Essays about: "fibrillation kinetics"

Found 3 essays containing the words fibrillation kinetics.

  1. 1. Fluorescent fusion proteins as probes to characterize tau fibril polymorphism

    University essay from Linköpings universitet/Kemi

    Author : Max Lindberg; [2019]
    Keywords : Alzheimer’s disease AD ; amyloids; FRET; tau; MAPT; fibrillation kinetics; seeding; fusion protein; EGFP; ECFP; EYFP; ThT; X-34; BTD14;

    Abstract : Alzheimer's disease (AD) is a large and growing problem and while we today lack a full understanding of this disease, we know that the protein tau and the amyloid fibrils it forms play a central role in its development. We also know that these fibrils can have different morphologies in different diseases and that fibrils produced in vitro not necessarily adopt any of the morphologies found in patients. READ MORE

  2. 2. Studies of Aβ aggregation, toxicity and cellular uptake

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Chiara Beretta; [2016]
    Keywords : Alzheimer’s disease; amyloid-beta; fluorescence; cellular uptake; labeling;

    Abstract : Alzheimer’s disease (AD) is the most common type of dementia observed in the elderly. The symptoms of the disease are provoked by neuronal loss caused by neurofibrillary tangles and amyloid plaques. The molecular processes that underlie AD’s pathology are at this day not well understood. READ MORE

  3. 3. Kinetic and Surface Properties of alpha-synuclein : Investigating the Difference between Pure Peptide and Phospholipid Including Aggregates

    University essay from Lunds universitet/Kemiska institutionen

    Author : Irem Nasir; [2011]
    Keywords : Nanokemi; Chemistry;

    Abstract : Popular summary Parkinson's Disease is a disorder caused by brain that affects patients' coordination, movement as well as causing tremor. The onset of Parkinson's Disease is found to be the large fibrillar aggregates in the brain which consists mostly alpha-synuclein protein. READ MORE