Essays about: "gene expression"

Showing result 11 - 15 of 469 essays containing the words gene expression.

  1. 11. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    University essay from Uppsala universitet/Neuroonkologi och neurodegeneration

    Author : Mathilda Stigenberg; [2023]
    Keywords : cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Abstract : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. READ MORE

  3. 12. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

    University essay from KTH/Proteinvetenskap

    Author : Alicia Bodin; [2023]
    Keywords : estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

    Abstract : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. READ MORE

  4. 13. Impact of BPA, BPF and Mixture N1 on DNA-Methylation of GRIN2B and NR3C1 during human neuroprogenitor cell differentiation

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Fysiologi och miljötoxikologi

    Author : Franziska Sophie Richter; [2023]
    Keywords : Epigenetics; Endocrine disrupting chemicals; DNA methylation; EDCs; Mixture effects; BPA; BPF; Mixture N1;

    Abstract : Endocrine disrupting chemicals (EDCs) are ubiquitous and their adverse impact on nature, wildlife and humans is extensively researched. We are constantly exposed to EDCs, such as the widespread and extensively researched Bisphenol A, as well as its substitute Bisphenol F, which is coming into wider use, even though it is much less is researched and limited information is available about its endocrine effects. READ MORE

  5. 14. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Yi Su; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE

  6. 15. Inferring Gene regulatory networks using Graph Neural Networks

    University essay from KTH/Genteknologi

    Author : Sohta Makino; [2023]
    Keywords : Graph Attention Network; Gene regulatory Network; Transcription; Data Science; Machine learning; Genreglering; transkription; dataanalys; Inferens; maskininlärning;

    Abstract : Inom beräkningsbiologin är det snabbt på väg att bli allt vanligare att ta fram genetiska regleringsnätverk (GRN). På grund av storleken på de undersökta nätverken använder många forskare maskininlärning för att härleda GRN från genuttrycksdata, vanligtvis från RNA-seq. READ MORE