Essays about: "gene technology"

Showing result 21 - 25 of 144 essays containing the words gene technology.

  1. 21. Review and Analysis of single-cell RNA sequencing cell-type identification and annotation tools

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Corentin Raoux; [2021]
    Keywords : Single-cell RNA sequencing; Automatic cell types annotation; Classification; Benchmark; Evaluation; Encells-RNA-sekvensering; Automatisk annotering av celltyper; Klassificering; Riktmärke; Värdering;

    Abstract : Single-cell RNA-sequencing makes possible to study the gene expression at the level of individual cells. However, one of the main challenges of the single-cell RNA-sequencing analysis today, is the identification and annotation of cell types. READ MORE

  3. 22. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Claudia De Guidi; [2021]
    Keywords : ;

    Abstract : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). READ MORE

  4. 23. Preparative chromatographyfor modified oligonucleotides : Method development for modified oligonucleotides, fromanalytical to preparative chromatography

    University essay from Karlstads universitet

    Author : Rebecka Jasinski; [2021]
    Keywords : oligonucleotides; preparative chromatography; scaling-up; ion-pair chromatography; dibutylamine; oligonukleotider; preparativ kromatografi; uppskalning; jonparskromatografi; dibutylamin;

    Abstract : Synthetic oligonucleotides, which are short strings of DNA or RNA, are a grooving area of importance for the pharmaceutical industry and for companies that manufacture diagnostic components. The manufacturing process of synthetic oligonucleotides involves many complex processes that use separation and purification techniques like ion-exchange chromatography, ion-pair reversed phase chromatography and ultra-performance liquid chromatography. READ MORE

  5. 24. Effect of doxorubicin exposure in breast cancer on single-cell level by scRNA-seq analysis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Núria Lladós Armengol; [2021]
    Keywords : ;

    Abstract : Doxorubicin is a highly effective chemotherapeutic agent against a variety of cancers; however, the exact mechanisms responsible for the effects of doxorubicin on cancer are not widely understood and have not been studied on a single-cell level. Single-cell RNA sequencing analysis is a recent technology that enables the assessment of transcriptional similarities and differences within a population of cells. READ MORE

  6. 25. Optimization of a sampling and analysis process to study the effects of skin care products on the microbial skin flora.

    University essay from Lunds universitet/Teknisk mikrobiologi

    Author : Emma Gifvars; [2021]
    Keywords : Method development; Method optimization; Microbial skin flora; Biotechnology; PCR analysis; Quantification of bacteria; Degree project in applied microbiology; Technology and Engineering; Biology and Life Sciences;

    Abstract : Vår hud är hem för en stor grupp av mikroorganismer, hudens mikroflora, som påverkar vår hälsa och vårt välbefinnande. Ändå finns det många aspekter av detta ämne som ännu är outforskade. READ MORE