Essays about: "gene therapy"

Showing result 1 - 5 of 42 essays containing the words gene therapy.

  1. 1. Non-coding RNAs as therapeutic agents : The future of therapy

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
    Keywords : Non-coding RNA; Oligonucleotide therapeutics;

    Abstract : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. READ MORE

  2. 2. Gene Expression Guided Distance Metric Learning for Breast Cancer Whole Slide Image Analysis

    University essay from Lunds universitet/Matematik LTH

    Author : Kajsa Ledesma Eriksson; [2022]
    Keywords : Whole Slide Image; Breast Cancer; Histopathology; Deep Metric Learning; Deep Learning; Image Analysis; Mathematics and Statistics;

    Abstract : Female breast cancer is a complex and heterogeneous disease that accounts for most of the deaths caused by cancer in women worldwide. To stratify breast cancer patients into treatment groups is a challenging task, and in recent years, analysis of the genes active in the tumour has been used in the decision of cancer therapy. READ MORE

  3. 3. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik

    Author : Marc Pielies Avellí; [2022]
    Keywords : Cancer Driver CD Gene; Histone Post-Translational Modifications PTMs ; Convolutional Neural Networks CNNs .; Physics and Astronomy;

    Abstract : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. READ MORE

  4. 4. Prediction of hub miRNAs and their associated pathways in Alzheimer's disease with miRNA-mRNA-TF network using bioinformatic tools

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Monika Kumari; [2021]
    Keywords : ;

    Abstract : The prevalence of Alzheimer’s in Europe is increasing strikingly over the past decade. Addressing this neurodegenerative disorder can be arduous as the underlying cause isn’t often reversible. READ MORE

  5. 5. Identification of novel loss of heterozygosity collateral lethality genes for potential applications in cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Margus Veanes; [2021]
    Keywords : biology; oncology; structural; genetics; bioinformatics; cancer;

    Abstract : Over the course of this project, I demonstrate the utility of a 4-phase analysis pipeline in the context of cancer therapy and the associated search for antineoplastic drug candidates. I showcase a repeatable means for generating lists of potential targets which may be used in conjunction with methods like small molecule screening as part of a search for broadly effective antineoplastic agents. READ MORE