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Showing result 1 - 5 of 18 essays matching the above criteria.
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1. Establishing novel approaches for assessing safety of genome-editing-based therapeutics
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Genome editing based medicines are a new therapeutic modality being developed. They show great promise for a spectrum of genetic diseases lacking conventional treatment strategies. A major obstacle that prevents such therapies to reach the clinic is their safety. READ MORE
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2. Compounds screening for the identification of novel drug to improve the Knock in efficiency mediated by CRISPR-Cas9
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Genome editing is an exciting field that allows for the precise modification of an organism's DNA. One of the most advanced tools in this area is CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9), which creates a DSB (Double-strand break) at a specific location in the genome. READ MORE
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3. mRNA-based pharmaceuticals : A literature study based on current knowledge of mRNA
University essay from Uppsala universitet/Institutionen för kemi - ÅngströmAbstract : This literature study provides a comprehensive overview of the current knowledge of mRNA-based pharmaceuticals, technologies and applications. mRNA-based pharmaceuticals have newly been bought into focus as a potential brand-new drug class and many believe that it has the potential to transform areas of medicine. READ MORE
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4. Exploration of the hereditary cause of sex ratio distortion in horses
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : Even sex ratios are seen as evolutionarily stable and are maintained by a selection against a skewed sex ratio. However, sometimes sex ratios at birth are skewed towards one sex. Reasons for this phenomenon are often unknown. READ MORE
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5. CRISPR AND THETREATMENT/EN DISTINCTION : On Vagueness, Borderline Cases and Germline Genome Editing
University essay from Umeå universitet/Institutionen för idé- och samhällsstudierAbstract : In this thesis, I argue that the treatment/enhancement distinction that is central to the ethical debate concerning germline genome editing and CRISPR is too vague to be ethically and normatively guiding. The problem of vagueness is twofold, being both a semantic and epistemic issue. READ MORE