Essays about: "genome-scale metabolic model GEM"

Found 2 essays containing the words genome-scale metabolic model GEM.

1. 1. Reconstruction of Genome-Scale Metabolic Models with Concomitant Constraint-Based Modelling for Flux Prediction – a Case Study of Syngas Consuming Hydrogenophaga pseudoflava

   University essay from Lunds universitet/Teknisk mikrobiologi

   Author : Cristopher Ollagnier Widén; [2020]
   Keywords : Applied Microbiology; flux-balance analysis FBA ; genome-scale metabolic model GEM ; Hydrogenophaga pseudoflava DSM 1084; KEGG; metabolic engineering; metabolic modelling; metabolic network reconstruction; RAVEN; syngas; systems biology; Technology and Engineering;

   Abstract : Metabolic modelling coupled with flux-balance analysis (FBA) has become a popular tool in systems biology for quantitative predictions of metabolic processes in silico, and as an aid in metabolic engineering. Drawing upon gene-protein-reaction associations deducible from information on the genome-level, so-called genome-scale metabolic models (GEMs) are unequalled in their scope as they attempt to encapsulate the entire reactome of a species or cell type. READ MORE

3. 2. Utilization of cancer-specific genome-scale metabolic models in pancreatic ductal adenocarcinomas for biomarkers discovery and patient stratification

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Mohamed Al Shobky; [2019]
   Keywords : Genome-Scale Metabolic Models; GEM; Pancreatic Ductal Adenocarcinomas; pancreatic cancer; cancer metabolism; biomarker; LDHA; L-lactate dehydrogenase A chain;

   Abstract : Pancreatic Ductal Adenocarcinomas initiates in the exocrine part of the pancreatic tissue and represents over 90% of all the pancreatic cancers. Pancreatic Ductal Adenocarcinomas are extremely aggressive and are one of the most lethal malignant neoplasms. The five-year relative survival is currently less than 8% of the patients. READ MORE