Essays about: "heterozygosity"
Showing result 1 - 5 of 25 essays containing the word heterozygosity.
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1. Analysis of relatedness and genetic diversity in Swedish sheep breeds using medium density (50K) SNP data
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : The local Swedish sheep breeds belong to a group of sheep breeds known as North European short-tailed sheep breeds. Evaluation of genetic diversity, relatedness, and population structure of local breeds offers crucial metrics to prevent inbreeding depression, genetic erosion, and crossbreeding between locally adapted and exotic sheep breeds since these occurrences can have detrimental effects and ultimately lead to extinction. READ MORE
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2. A bear-y strong comeback: Investigating temporal genomic consequences of a recent demographic bottleneck in the Scandinavian brown bear
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : The Scandinavian brown bear went through a severe bottleneck due to human actions in the early 1900’s that reduced the population to low numbers. After protective measures were taken, the population recovered and today it consists of around 3000 individuals. READ MORE
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3. CYP2D6 loss of heterozygosity - a potential target for neuroblastoma therapy
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Loss of heterozygosity events, whereby alleles are lost at heterozygous chromosomal loci, are associated with cancer formation and may result in the deletion of numerous genes encoding enzymes that have critical activities within the cell. Consequently, vulnerabilities are created that are absent in normal cells which can be targeted using a precision medicine approach called collateral lethality. READ MORE
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4. Genomic diversity analysis in the Swedish Landrace Goat
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : There are four goat breeds present in Sweden. However, no genetic studies were dedicated to investigating the genetic diversity in these breeds. This thesis therefore aims to describe the population structure and the level of inbreeding in the goat breed with the largest population number, the Swedish Landrace goat. READ MORE
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5. Inavelsgrad i stängda stamböcker : en high density SNP analys av fem svenska fårraser
University essay from SLU/Dept. of Biosystems and Technology (from 130101)Abstract : Med hjälp av high density SNP, en metod för att kartlägga basparspolymorfism, undersöktes släktskap och inavelsgrad hos fem svenska fårraser. Inavelsgraden undersöktes med avseende på heterozygoti samt antal och längd för s.k. runs of homozygosity (ROH). READ MORE