Essays about: "homeostasis"

Showing result 1 - 5 of 53 essays containing the word homeostasis.

  1. 1. Medication-related osteonecrosis of the jaws initiated by zoledronic acid, potential pathophysiology. A systematic review

    University essay from Malmö universitet/Odontologiska fakulteten

    Author : Aya Al-Salih; Annica Dam; [2020]
    Keywords : Läkemedelsrelaterad osteonekros i käkarna; patofysiologi; zoledronat; zoledronsyra.;

    Abstract : Syfte: Syftet med den systematiska översikten är att granska och sammanställa tillgänglig kunskap om cellulära mekanismer involverade i utvecklingen av läkemedelsrelaterad osteonekros i käkarna orsakad av zoledronsyra. Material och metod: En systematisk översikt. READ MORE

  2. 2. Activation of NLRP3 inflammasome leads to the differential secretion of interleukins 1*/18 possibly linked to pyroptosis in THP-1 cells

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Jana Damiani; [2020]
    Keywords : ;

    Abstract : Organisms are constantly exposed to microorganisms, some of which can cause disease, and yet, sickness only rarely occurs. Upon infection, the immune system is mobilized to eliminate the threat and re-establish homeostasis. READ MORE

  3. 3. Inhibitory effect on the proteasome regulatory subunit, RPN11/POH1, with the use of Capzimin-PROTAC to trigger apoptosis in cancer cells

    University essay from Linköpings universitet/Kemi

    Author : Andreas Holmqvist; [2020]
    Keywords : Proteolysis targeting chimera PROTAC ; Cancer therapeutics; Ubiquitin proteasome system UPS ; Cancer; Chemotherapy; Proteasome inhibitor; Capzimin;

    Abstract : Most patients diagnosed with cancer will receive systematic chemotherapy at some point during their illness, which almost always cause severe side effects for the patients such as, anemia, nausea and vomiting. The problems with today’s chemotherapy is not only that it cause severe side effects, but also that the cancer may develop resistance to the therapy, which is why the development of a new type of therapeutic agent is in dire need. READ MORE

  4. 4. Purification, functional characterization and crystallization of the PerR peroxide sensor from Saccharopolyspora erythraea

    University essay from Uppsala universitet/Strukturbiologi

    Author : Grim Elison Kalman; [2019]
    Keywords : structural biology; cell culture; protein expression; genetic engineering; spectroscopy; X-ray crystallography; small angle X-ray scattering; SAXS; transcription factor; PerR; metal binding; antibiotics; Saccharopolyspora erythraea; S. erythraea; soil bacterium; actinobacteria; actinomycetes; oxidative stress; peroxide stress; structure determination; characterization; stabilization; peroxide sensor; iron sensor; manganese sensor; metalloprotein; metal ion homeostasis; metal ion; prokaryotic; strukturbiologi; cellodling; proteinuttryck; genteknik; spektroskopi; röntgenkristallografi; småvinkel-röntgenspridning; SAXS; transkriptionsfaktor; PerR; metallbindande; antibiotika; Saccharopolyspora erythraea; S. erythraea; jordartsbakterie; Aktinobakterier; Actinobacteria; Actinomycetes; oxidativ stress; peroxid stress; strukturbestämning; karaktärisering; stabilisering; peroxidsensor; järnsensor; mangansensor; metalljonshomeostas; metalljoner; prokaryot;

    Abstract : This report summarizes the work on the cloning, expression, and purification of PerR, a metal sensing regulator from Saccharopolyspora erythraea and the subsequent characterization using small angle X-ray scattering and other biochemical methods. The report aims to provide an insight into prokaryotic metal homeostasis, provide a better understanding of how PerR works and provide valuable information for the continued work on the crystallization of PerR. READ MORE

  5. 5. Exercise-induced cardiac remodeling : a potential cause of pathological changes in the equine heart?

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Maria Neil; [2019]
    Keywords : Cardiac remodeling; equine; horse; exercise; hypoxia; valvular regurgitation; cardiac murmur; atrial fibrillation;

    Abstract : Cardiac remodeling is a response to exercise that has been reported in a number of different species. Intensified training will lead to an increasing demand on the cardiovascular capacity, because of the requirements of enhanced oxygen delivery, metabolism and thermoregulation. READ MORE