Essays about: "huntingtin lowering"

Found 1 essay containing the words huntingtin lowering.

  1. 1. Huntingtin gene profiling, towards allele-specific treatment

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Mimmi Håkansson; [2020]
    Keywords : Huntington’s disease; huntingtin lowering; allele-selective; HD animal models; Huntingtons sjukdom; huntingtin sänkning; allel-specifik; Huntington djurmodeller;

    Abstract : Huntington diseases(HD) is a fatal autosomal neurodegenerative genetic disorder, caused by a CAG trinucleotide repeat expansion in the huntingtin (HTT) gene, resulting in a toxic gain-of-function in the mutant huntingtin protein(mHTT). To date, there is no approved treatment to either cure or halt the course of HD. READ MORE