Essays about: "hypoxia-inducible factors"

Found 2 essays containing the words hypoxia-inducible factors.

1. 1. Hypoxia and hematopoietic stem cell control with the substance Adaptaquin : An evaluation of hematopoietic stem cell’s proliferation and differentiation in artificially induced hypoxia

   University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

   Author : Jens Christiansen; [2023]
   Keywords : Adaptaquin; Flow cytometry; Hematopoietic stem cells; Hypoxia; Hypoxia inducible factor; Prolyl hydroxylase; Adaptaquin; Flödescytometri; Hematopoetiska stamceller; Hypoxi; Hypoxi inducerande faktor; Prolylhydroxylas;

   Abstract : Hematopoietic stem cells (HSCs) have historically been difficult to maintain ex vivo with many attempts to culture them in vitro by mimicking their natural biological environment. Providing a hypoxic environment is one way to achieve this goal and can be performed by using hypoxia stimulating compounds that inhibits the degradation of HIF1a which plays an important role in regulating hypoxia. READ MORE

3. 2. Assessing the relationship between hypoxia and life on Earth, and implications for the search for habitable exoplanets

   University essay from Lunds universitet/Geologiska institutionen

   Author : Thomas Evan Smith; [2022]
   Keywords : hypoxia; hypoxia-inducible factors; atmospheric oxygen; multicellularity; embryogenesis; exoplanets; white dwarfs; oxygen fugacity; Earth and Environmental Sciences;

   Abstract : Atmospheric oxygen at the level of present-day Earth (21%) is generally regarded as permissive for the development and survival of complex multicellular life, such as animals. The hypothesis that oxic conditions are conducive for multicellular life has subsequently been applied to the search for life elsewhere in the universe, with planets exhibiting atmospheric oxygen of a similar level to Earth being considered as candidates for habitability. READ MORE