Essays about: "imipenem"

Found 4 essays containing the word imipenem.

  1. 1. The Binding Mechanism of Carbapenems in the Class A beta-lactamase IMI-1 : A Molecular Dynamics Study of Ligand Stability

    University essay from Uppsala universitet/Biokemi

    Author : Isabell Lindahl; [2022]
    Keywords : antibiotic resistance; IMI-1; betalactamase; Carbapenemase; free energy; LIE; linear interaction energy; β-lactamase; meropenem; biapenem; imipenem; active site;

    Abstract : Antibiotic resistance is a global and accelerating matter. Over time, the bacteria have evolved several defense mechanisms against the antibiotics. One of the defense mechanisms is that the bacteria can produce enzymes with the ability to hydrolyze the characteristic b-lactam ring of the antibiotics. These enzymes are called b-lactamases. READ MORE

  3. 2. An Investigation of Cefadroxil and Meropenem’s Supply Chain and Estimationof the Health Economic Consequences in Sweden due to Shortage

    University essay from Uppsala universitet/Institutionen för kemi - Ångström

    Author : Christine Attemalm; Jonathan Efverström; Dania Elkhalifa; Viktor Hansen; Yasmine Sundelin Tjärnström; [2020]
    Keywords : cefadroxil; meropenem; supply chain; backorders; Swedish healthcare;

    Abstract : Sweden has been increasingly affected by drug shortage and the public healthcare system has identified a large amount of antibiotics risking shortage. Drug shortage of antibiotics is a worldwide problem with complex causes and consequences affecting many countries healthcare systems. READ MORE

  4. 3. Optimization of CarG crystals : a protein involved in the biosynthesis of 1-carbapen-2-em-3-carboxylic acid (Car); a beta-lactam antibiotic

    University essay from SLU/Dept. of Molecular Biology (until 131231)

    Author : Teres Persson; [2012]
    Keywords : carbapenem; CarG; optimization; purification; crystallography;

    Abstract : Carbapenems are one of the most widely used groups of antibiotics because of their broad spectrum against both gram positive and gram negative bacteria. The biosynthesis of the simplest carbapenem, 1-carbapen-2-em-3- carboxylic acid (Car) is controlled by an operon of eight genes, CarA-H. READ MORE

  5. 4. Potential aquatic bacterial pathogens in thePhilippines and Thailand : studies on the occurrence, characterisation, detection ofpotential virulence determinants and antimicrobialsusceptibility profile

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Ramon Maluping; [2004]
    Keywords : Aeromonas spp.; Vibrio spp.; P. shigelloides; Philippines; Thailand; virulence determinants; antimicrobial susceptibility;

    Abstract : Strains of Aeromonas spp., `non–cholera vibrios´(NCVs) and Plesiomonas shigelloides isolated from aquatic environments and fish and human diarrhoeal cases in the Philippines and Thailand were characterised for potential virulencemarkers, such as the production of cytotoxin, cell-associated and cell-free haemolysin and their capacity to adhere to human intestinal (Henle 407) cells invitro. READ MORE