Essays about: "immunity genes"

Showing result 1 - 5 of 13 essays containing the words immunity genes.

1. 1. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

   University essay from Uppsala universitet/Neuroonkologi och neurodegeneration

   Author : Mathilda Stigenberg; [2023]
   Keywords : cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

   Abstract : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. READ MORE

3. 2. Regulation of Plant Defense Genes Against Bacterial Pathogens

   University essay from KTH/Proteinvetenskap

   Author : Jenny Sjöström; [2021]
   Keywords : plant defense; PTI; FLS2; SERK1; regulation; växtförsvar; PTI; FLS2; SERK1; reglering;

   Abstract : Sjukdom på grödor orsakad av bakterier kan bidra till ekonomiska förluster för bönder samt brist på mat, därför är det viktigt att utveckla nya hållbara sätt att motverka och behandla grödor mot bakterier. Idag är det mest vanliga tillvägagångssättet antibiotika men detta är inte hållbart p.g.a uppkomst av antibiotikaresistens. READ MORE

4. 3. Characterizing the immunogenic cell death induced by Semliki Forest Virus in glioblastoma cell lines

   University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologi; Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Aishwarya Sivaramakrishnan; [2021]
   Keywords : Glioblastoma; Immunogenic Cell Death; Oncolytic Viruses; Semliki Forest Virus; Aishwarya Sivaramakrishnan;

   Abstract : Glioblastoma is the most common primary brain tumor in humans and has a poor prognosis. Current therapies are not curative. Oncolytic viruses (OVs) are being investigated as tools to induce immunogenic cell death (ICD), cell death capable of activating the immune system. READ MORE

5. 4. Design, expression and purification of virus-like particles derived from metagenomic studies : Virus-like Particles (VLP) of novel Partitiviridae species, Hubei.PLV 11, and novel Soutern pygmy squid flavilike virus were designed, expressed using the bac-to-bac expression system and then pruified using various methods

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Diyar Ayranci; [2021]
   Keywords : Virus; virus-like particles; VLP. Western Blot; SDS-PAGE; Chromatography; partitivrus; partitiviridae; flaviviridae; flavivirus; Hubei partitilike virus; Southern Pygmy Squid flavilike virus; protein purification; protein characterization; PCR; Cloning; metagenomic; strucutral biology; cryo-em; bac-to-bac expression system; vaccines; arbovirus; arthropod-borne virus;

   Abstract : Viruses are entities which are made of a few genes and are reliant on obligate parasitism to propagate. Due to the obligate connection to their hosts, virus evolution is constrained to the type of host. Viruses however do transmit to evolutionary distinct hosts; in these cases, the phylogenetic relationship of the hosts usually are close. READ MORE

6. 5. Characterization of MITF gene in crayfish and their possible role in innate immunity

   University essay from SLU/Dept. of Animal Breeding and Genetics

   Author : Yaru Wen; [2020]
   Keywords : Microphthalmia-associated transcription factor; basic Helix-Loop-Helix Leucine Zipper; crayfish; Aphanomyces astaci; immunity;

   Abstract : Microphthalmia-associated transcription factor (MITF) is a tissue-specific transcription factor (TF), with a basic helix-loop-helix leucine zipper (bHLH-LZ) domain, which binds to the canonical E-box sequence (5’-CANNTG-3’) in the promoter region of target genes. In this study, the MITF-like protein was identified in the marbled crayfish (Procambarus virginalis). READ MORE