Essays about: "immunoassay"

Showing result 1 - 5 of 46 essays containing the word immunoassay.

  1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Sam Vadi Dris; [2024]
    Keywords : Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

    Abstract : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. READ MORE

  3. 2. Development of specific host cell protein assays

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Anna Ivert Nordén; [2023]
    Keywords : Gyrolab; Immunoassay; HCP;

    Abstract : The manufacturing and the development of biotherapeutic drugs involves the expression of biotherapeutic proteins in a host cell expression system followed by a purification process. Bioanalytical methods to measure impurities such as host cell proteins (HCPs) are needed to obtain a robust process and a safe drug according to regulatory requirements. READ MORE

  4. 3. Increased system sensitivity using fluorescent based immunoassays on the Gyrolab® platform

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Gabriel Lisra; [2023]
    Keywords : Gyrolab; fluorescence; sensitivity; immunoassays;

    Abstract : Immunoassays have become an essential tool in several fields of bioanalytics with tremendous advances in sensitivity and formats seen through the last three decades. Many diseases are today diagnosed solely based on biomarker concentrations evaluated through immunoassays. READ MORE

  5. 4. Serum TK1 activity and SAA concentration as biomarkers to differentiate lymphoma from gastrointestinal disease in cats

    University essay from SLU/Dept. of Clinical Sciences

    Author : Amanda Friman; [2023]
    Keywords : lymphoma; gastrointestinal lymphoma; feline lymphoma; inflammatory bowel disease; IBD; thymidine kinase 1; TK1; biomarker; cancer; cats;

    Abstract : Alimentary lymphoma is one of the most common malignant neoplasms in the gastrointestinal (GI) tract in cats. Since the clinical signs often are identical to those of inflammatory bowel disease (IBD), and the findings on diagnostic imaging and endoscopic mucosal biopsies overlap, invasive biopsy sampling from the GI tract is needed to be able to differentiate these two diseases from each other. READ MORE

  6. 5. Implementation of an automatic tangential flow filtration system for latex immunoassay production

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Filippa Stolpe; Sofia Kullander; [2023]
    Keywords : biotechnology; bioprocess; diagnostics; production; TFF; tangential flow filtration; blood clots; automation; antibodies; latex immunoassay; LIA;

    Abstract : To diagnose patients suffering from blood clotting disorders latex immununoassays (LIA) can be used. A time consuming manual tangential flow filtration (TFF) process suggests the implementation of an automatic TFF system to improve the efficiency, profitability, and expandability of the production facility of LIA at Nordic Biomarker. READ MORE