Essays about: "interfering RNA"

Showing result 1 - 5 of 8 essays containing the words interfering RNA.

1. 1. Non-coding RNAs as therapeutic agents : The future of therapy

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
   Keywords : Non-coding RNA; Oligonucleotide therapeutics;

   Abstract : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. READ MORE

3. 2. A novel Adenoviral miRNA, a candidate for development of a novel gene therapy startegy

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Benjamin Danish; [2019]
   Keywords : A novel Adenoviral miRNA;

   Abstract : In 2017, a novel miRNA was found at the MLTU-region of adenoviral genome, termed as MLP-TSS-sRNA. This current study started with performing a series of mutations in the MLP-TSS-sRNA in order to investigate how the MLP-TSS-sRNA as a single stranded small RNA was protected from rapid RNA degradation in transfected cells (in vivo). READ MORE

4. 3. A Survey of Commercial Biomolecules, Delimited to Pharmaceuticals and Medical Devices

   University essay from Uppsala universitet/Institutionen för teknikvetenskaper

   Author : Alberto Martinez; Nadia Mohammadi; Markus Holowacz; Annika Krans; Camilla Wallén; [2017]
   Keywords : Biologics;

   Abstract : Biologics — biomolecule-based therapeutics — are predicted to become the next generation of therapeutical drugs. The pharmaceutical industry is investing a great amount of money into research in this medical field, which shows the importance and the need of analyses regarding biological drugs. READ MORE

5. 4. A Survey of Commercial Biomolecules, Delimited to Pharmaceuticals and Medical Devices

   University essay from Uppsala universitet/Institutionen för teknikvetenskaper

   Author : Markus Holowacz; Annika Krans; Camilla Wallén; Alberto Martinez; Nadia Mohammadi; [2017]
   Keywords : Biologics;

   Abstract : Biologics — biomolecule-based therapeutics — are predicted to become the next generation of therapeutical drugs. The pharmaceutical industry is investing a great amount of money into research in this medical field, which shows the importance and the need of analyses regarding biological drugs. READ MORE

6. 5. Exploring the effects of platinum compounds on RNA, adduct formation, thermal melting properties and siRNA down regulation capacity of gene targets associated

   University essay from Lunds universitet/Kemiska institutionen

   Author : Alak Al Shiekh; [2012]
   Keywords : Proteinvetenskap; Chemistry;

   Abstract : Since its discovery, RNA interference (RNAi) has turned into an invaluable research tool for regulating gene expression. Furthermore, this naturally occurring phenomenon in mammalian cells is of interest in cancer research, both as a possible therapeutic approach and a target for cancer treatment. READ MORE