Essays about: "ion-pair chromatography"

Found 4 essays containing the words ion-pair chromatography.

  1. 1. A study of the adsorption isotherms of Ion-pair reagents

    University essay from Karlstads universitet

    Author : Mehmet Bilici; [2022]
    Keywords : Tributylamine; adsorption isotherm; liquid-liquid extraction; gas chromatography;

    Abstract : In this project, the optimization of obtaining adsorption isotherms for the ion pair reagent, tributylamine was tested. The goal was to have a better understanding of the chromatographic process when separating biomolecules, such as oligonucleotides. READ MORE

  2. 2. A Comparative Analysis of Per- andPolyfluoroalkyl Substances (PFAS) and ExtractableOrganofluorine (EOF) Using Solid PhaseExtraction-Weak Anion Exchange and Ion PairExtraction in SerumMarichal SalamehSpring 2021Independent project

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Marichal Salameh; [2021]
    Keywords : Extractable organofluorine EOF ; Per- and polyfluoroalkyl substances PFAS ; horse serum; human serum; ion pair extraction IPE ; solid phase extraction - weak anion exchange SPE-WAX ; liquid chromatography tandem mass spectrometry LC-MS MS ; combustion ion chromatography CIC ;

    Abstract : Per- and polyfluorinated substances (PFAS) are compounds that consist of a carbon chainbackbone that is partially or entirely fluorinated, with an addition of a functional group. SomePFAS are known as persistent organic pollutants (POPs) and have therefore been drawing a lot ofattention as well as increased concerns. READ MORE

  3. 3. Preparative chromatographyfor modified oligonucleotides : Method development for modified oligonucleotides, fromanalytical to preparative chromatography

    University essay from Karlstads universitet

    Author : Rebecka Jasinski; [2021]
    Keywords : oligonucleotides; preparative chromatography; scaling-up; ion-pair chromatography; dibutylamine; oligonukleotider; preparativ kromatografi; uppskalning; jonparskromatografi; dibutylamin;

    Abstract : Synthetic oligonucleotides, which are short strings of DNA or RNA, are a grooving area of importance for the pharmaceutical industry and for companies that manufacture diagnostic components. The manufacturing process of synthetic oligonucleotides involves many complex processes that use separation and purification techniques like ion-exchange chromatography, ion-pair reversed phase chromatography and ultra-performance liquid chromatography. READ MORE

  4. 4. The impact of various chromatographic conditions on the separation of modified and unmodified oligonucleotides

    University essay from Karlstads universitet

    Author : Lewis Frazer; [2021]
    Keywords : Oligonucleotide; Modified oligonucleotides; Ion-pair chromatography; Chromatography; Analytical chemistry; TEAA; DBA; Chemistry; Oligonukleotid; Modifierade oligonukleotider; Jonpars kromatografi; Kromatografi; Analytisk kemi; TEAA; DBA; Kemi;

    Abstract : In this study, the effects of certain chromatographic conditions on various modified and unmodified oligonucleotides were investigated. At the forefront of this study was the investigation of a new Ion-pair Reversed-phase liquid chromatography (IP-RPLC) method, that had the potential to replace a previously established triethylammonium acetate (TEAA) IP-RPLC method developed for oligonucleotide separations. READ MORE