Essays about: "knock-out mice"
Showing result 1 - 5 of 7 essays containing the words knock-out mice.
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1. Possible interaction of sympathetic nerves with macrophages via fractalkine-CX3CR1 ligation in pancreatic islets
University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi; Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Disturbing the interaction between sympathetic nerves and macrophages in islets has been shown to protect from insulitis development. To study the intra-islet neuroimmune communications, we explored the interactions between macrophages and nerves in the islets by looking at their juxta-positioning in the islets of wild type and CX3CR1 knock out mice. READ MORE
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2. The role of exosomes in sarcoidosis
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Sarcoidosis is a systemic inflammatory disease mostly affecting the lungs, marked by the presence of granulomas and the accumulation of interferon gamma (IFNγ)-producing T cells in the affected organs. Extracellular vesicles (EVs) are membranous vesicles with a size range of 50 nm to 5000 nm, with exosomes ranging from 50 to 150 nm. READ MORE
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3. A pericyte-specific knockout of Foxf2 in mice shows fibrinogen acculumation in the brain but no regulation in Pdgfr-ß expression
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : FoxF2 is a transcriptional factor that initiates gene expression. Foxf2 is particularly expressed in central nervous system pericytes. Recent studies have displayed that an inactivation of Foxf2 in mice had an impact on the blood-brain barrier integrity with evidence of breakdown. READ MORE
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4. Adipocytes from SERCA2 knockout mice exhibit a dysregulation in the secretion of adiponectin and resistin
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Obesity leading to Type-2-diabetes is a major health issue all over the world. Obesity characterized by expansion of adipose tissue, in particular white adipose tissue (WAT) which controls the metabolic physiology in the body by secreting proteins like adiponectin and resistin. READ MORE
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5. Colitis-Associated Colorectal Cancer in Mice: In vivo Disease Imaging and Insight into the AOM/DSS Model
University essay from Lunds universitet/Tillämpad biokemiAbstract : Inflammatory bowel diseases as ulcerative colitis and Cohn’s disease represent significant health problems in the western world. Colon cancer is a common consequence of those chron- ic inflammatory disorders, thereby it is essential to improve knowledge and research level of this area. READ MORE
