Essays about: "kynurenine"
Found 1 essay containing the word kynurenine.
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1. A1M, Hb and tryptophan metabolism in R6/2 mouse model of Huntington’s disease
University essay from Lunds universitet/LäkarutbildningenAbstract : Neurotoxic metabolites generated from tryptophan metabolism are increasingly regarded as a pathogenic mechanism in neurological and psychiatric disease including Huntington’s disease (HD). Specifically, the tryptophan-derived neurotoxin 3-hydroxykynurenine (3-HK) accumulates in HD brain and is capable of damaging neurons through excessive ROS-production and oxidative stress. READ MORE
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