Essays about: "lipid nanoparticles"
Showing result 1 - 5 of 8 essays containing the words lipid nanoparticles.
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1. Exploring alternative surfactants to replace PEG within lipid nanoparticles
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE
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2. Comparison and optimization of extracellular vesicle (EV) capturing on functional thin films for their molecular profiling
University essay from KTH/Tillämpad fysikAbstract : Extracellular vesicles (EVs) are lipid bilayer encapsulated nanoparticles which have emerged as an excellent source of biomarkers for multiple diseases, including cancer. However, they are highly heterogeneous in their molecular compositions which remains a major challenge hindering the utilization of their biomarker potential. READ MORE
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3. Optimising microfluidic preparation of lipid sponge phase nanoparticles for biomolecule encapsulation
University essay from Lunds universitet/Kemiteknik (CI)Abstract : Drug delivery with lipid nanoparticles, especially sponge phase lipid nanoparticles (LNP), has been well studied because of its ability for drug encapsulation and transferring the drug through the cell membrane. The sponge phase LNP formulation could be affected by the molecular structure of the lipid, the temperature, pH, dilution, the buffer, and the addition of a stabiliser. READ MORE
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4. Affibody phage display selections for lipid nanoparticle and affibody-mediated transient CAR T-cell therapy
University essay from KTH/ProteinvetenskapAbstract : CAR T-cellbehandling är en immunterapi som har visat lovande resultat vid behandling av cancer. Trots det riktade immunsvaret som kan uppnås, betonar komplexiteten i tillverkningsprocessen och behandlingsproceduren det utrymme somm finns för förbättringar. READ MORE
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5. Exosomes and lipid nanoparticles - the future of targeted drug delivery
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : In this project an overview of how synthetic lipid nanoparticles and exosomes can be used for targeted drug delivery is compiled. The goal is to identify aspects that can be in favor for targeted drug delivery and the development of products at Cytiva. READ MORE