Essays about: "liquid column"

Showing result 1 - 5 of 23 essays containing the words liquid column.

  1. 1. Optimization of a Methodology for Cell Based Untargeted Metabolomics with UHPLC-Q-ToF-MS

    University essay from Uppsala universitet/Analytisk farmaceutisk kemi

    Author : Jens Westerinen; [2020]
    Keywords : ;

    Abstract : Metabolomics is the study of small molecules (molecular weight < 1500 Da) in a biological system and can provide relevant information about endpoints of biochemical pathways by establishing metabolic profiles for different sample cohorts and comparing these through multivariate data analysis. The aim of this thesis was to establish and test a suitable methodology for cell-based untargeted metabolomics, utilizing UHPLC-MS. READ MORE

  2. 2. Automated Simulation and Parameter Estimation of Chromatography Processes

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Johan Olsson; [2019]
    Keywords : chemical engineering; kemiteknik; Technology and Engineering;

    Abstract : Preparative chromatography is an important separation technique in downstream processing for several industries. It has the ability to separate two or more component from each other to achieve high purity. READ MORE

  3. 3. Development of separation method for analysis of oligonucleotides using LC-UV/MS

    University essay from Uppsala universitet/Analytisk farmaceutisk kemi

    Author : Björs Ida; [2018]
    Keywords : Oligonucleotides; UPLC; liquid chromatography; time of flight; mass spectrometry; reversed-phase weak anion exchange; AcclaimTM Mixed Mode WAX-1; DNAPacTM RP; ACQUITY UPLC BEH C18;

    Abstract : Introduction Oligonucleotides are short nucleic acid chains, usually 19-27mer long. They bind to their corresponding chain, making a specific inhibition possible. In pharmaceuticals, this can be used to inhibit the expression of a gene or protein of interest. READ MORE

  4. 4. Comparison of two HPLC columns: An attempt to improve analysis of carbohydrate-deficient transferrin

    University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Author : Ida Engström; [2018]
    Keywords : Reprospher; liquid chromatography; ion exchange chromatography; CDT; gradient elution;

    Abstract : 1ABSTRACTCarbohydrate-deficient transferrin (CDT) is a biomarker for excessive and long-running intake of alcohol. It is a form of transferrin called disialotransferrin that under normal circumstances is <2 % of total transferrin in human blood. An increase is seen when alcohol consumption exceeds450 g per week. READ MORE

  5. 5. Prediction of Ranking of Chromatographic Retention Times using a Convolutional Network

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Daniel Kruczek; [2018]
    Keywords : Shotgun proteomics; retention time; retention time prediction; neural networks; convolutional neural networks;

    Abstract : In shotgun proteomics, the liquid chromatography step is used to separate peptides in order to analyze as few as possible at the same time in the mass spectrometry step. Each peptide has a retention time, that is how long it takes to pass through the chromatography column. READ MORE