Essays about: "mRNA design"
Showing result 1 - 5 of 9 essays containing the words mRNA design.
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1. mRNA-based pharmaceuticals : A literature study based on current knowledge of mRNA
University essay from Uppsala universitet/Institutionen för kemi - ÅngströmAbstract : This literature study provides a comprehensive overview of the current knowledge of mRNA-based pharmaceuticals, technologies and applications. mRNA-based pharmaceuticals have newly been bought into focus as a potential brand-new drug class and many believe that it has the potential to transform areas of medicine. READ MORE
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2. Increased expression of therapeutic proteins by identification of 3'-UTRs from high expressing genes in CHO cells
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : Therapeutic proteins, a.k.a. biopharmaceuticals, are most commonly produced in expression systems derived from Chinese Hamstery Ovary (CHO) cells, thanks to great capacity of post-translational modifications like secretation, folding and glycosylation. READ MORE
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3. Impact of maternal smoking onmRNA expression in placental tissue : - a systematic literature survey
University essay from Örebro universitet/Institutionen för medicinska vetenskaperAbstract : Introduction: Maternal smoking during pregnancy is becoming less common. However, it is still a significant predictor of adverse outcomes. Smoking during pregnancy has been associated with impaired fetal development and growth. READ MORE
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4. A Statistical Framework for Classification of Tumor Type from microRNA Data
University essay from KTH/Matematisk statistikAbstract : Hepatocellular carcinoma (HCC) is a type of liver cancer with low survival rate, not least due to the difficulty of diagnosing it in an early stage. The objective of this thesis is to build a random forest classification method based on microRNA (and messenger RNA) expression profiles from patients with HCC. READ MORE
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5. Structural elucidation of mRNA(Sirt1)-microRNA 34a complex
University essay from KTH/Skolan för teknikvetenskaplig kommunikation och lärande (ECE)Abstract : The aim of this thesis is to understand RNA-RNA interactions steering cellular functions, as in the case of this thesis the structure of mRNA(Sirt1) in complex with microRNA-34a (miR-34a). MiR-34a regulates the cancer protein p53 via Sirt1 modulation. READ MORE