Essays about: "mRNA"

Showing result 1 - 5 of 140 essays containing the word mRNA.

  1. 1. Studying gene expression scaling with cell size in Arabidopsis thaliana : the role of the nuclear RNA exosome complex

    University essay from SLU/Dept. Of Plant Biology

    Author : Emily Tåhlin; [2024]
    Keywords : RNA; transcription; cell size; smFISH; Arabidopsis thaliana;

    Abstract : The scaling of organ size with body size - known as morphological allometry - is a fundamental mechanism observed in all organisms (Mirth et al. 2016). READ MORE

  3. 2. Exploring alternative surfactants to replace PEG within lipid nanoparticles

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)

    Author : Elina Edidovica; [2024]
    Keywords : Lipid nanoparticle; polyethelyne glycol PEG ; alpha-tomatine; N-hexadecyl beta d-maltoside HDM ; DOPC; DPPC; cholesterol; film hydration; stability study; DLS; Cryo-TEM; SAXS; pharmaceutical formulation; Chemistry;

    Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE

  4. 3. The Quantitative Expression of Transport Proteins SLC38A1-11 in Nerve Cell Development

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Maryam Dinar; [2023]
    Keywords : SLC38A1; SNAT1; SLC38A2; SNAT2; SLC38A3; SNAT3; SLC38A4; SNAT4; SLC38A5; SNAT5; SLC38A6; SNAT6; SLC38A7; SNAT7; SLC38A8; SNAT8; SLC38A9; SNAT9; SLC38A10; SNAT10; SLC38A11; SNAT11; SLC; SLC38; SNATs; SNAT; RT-qPCR; GABA; glutamine; glutamate;

    Abstract : Solute carriers consist of over 400 genes and 66 subfamilies and are the largest group of membrane bound transporters. They facilitate movement of many molecules through cells and organelles and are crucial for upholding many key functions in the human body. They are also involved in the pathophysiology of several diseases. READ MORE

  5. 4. PAMPaR: Parallel Analysis of miRNAs, Proteins and RNAs. Dynamic Profiles of miRNAs, mRNAs and Specific Proteins in Mouse Embryonic Stem Cells Differentiating into Neural Precursors

    University essay from KTH/Proteinvetenskap

    Author : Amelie Carlström; [2023]
    Keywords : PAMPaR; SPARC; Proximity extension assay; Neuronal differentiation; Mouse embryonic stem cells; PAMPaR; SPARC; Proximity extension assay; Neuronal differentiering; embryonala musstamceller;

    Abstract : MikroRNA-molekyler (miRNA) är viktiga icke-kodande RNA-molekyler för post-transkriptionell reglering av proteinkodande gener. De har även effekter på många cellulära processer såsom differentiering. De biosyntetiska reaktioner som skapar miRNA involverar proteiner som själva regleras av miRNA. READ MORE

  6. 5. Exploratory study of ion pair liquid chromatography separation methods and sample preparation procedures – for quantification of amount 5’capped and uncapped mRNA

    University essay from Karlstads universitet/Institutionen för ingenjörs- och kemivetenskaper (from 2013)

    Author : Felicia Lindström; [2023]
    Keywords : ;

    Abstract : Using ion pair chromatography, separation and analysis of shorter mRNA fragments was possible. The aim of the study was to develop a separation method for quantitation of 5’capped versus uncapped mRNA. Cleavage of mRNA was performed by complementary probes and the enzyme RNase H which created shorter mRNA fragments containing the 5’ end. READ MORE