Essays about: "malignant glioma"

Showing result 1 - 5 of 6 essays containing the words malignant glioma.

  1. 1. Identification of Immunological Targets for Brain Cancer Immunotherapy

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Zhenda Wang; [2022]
    Keywords : Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Abstract : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. READ MORE

  3. 2. Treatment outcomes on malignant gliomas using oncolytic viruses

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Pegah Tehranipour; [2020]
    Keywords : oncolytic virus; malignant glioma; reovirus; parvovirus;

    Abstract : Purpose: The objective of this thesis is to evaluate clinical studies that have used oncolytic viruses as treatment and to compare their treatment-outcomes on patients with malignant glioma. Method: This thesis is a systematic literature review where PubMed has been used as the database for data collection. READ MORE

  4. 3. Investigation of RRM2 as a potential therapeutic target against glioblastoma

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Neda Hekmati; [2017]
    Keywords : cancer; glioblastoma; RRM2;

    Abstract : Title: Investigation of RRM2 as a potential therapeutic target against glioblastoma Supervisors: Dr. Sven Nelander and Mr. Sathishkumar Baskaran. READ MORE

  5. 4. Dental Mesenchymal Stem Cells’ Effect on Glioma Cells

    University essay from Umeå universitet/Institutionen för odontologi

    Author : Paulina Tseng; Oscar Hedlund; [2017]
    Keywords : ;

    Abstract : Glioma is a malignant tumor with a high mortality rate within few years of diagnosis. Due to limited effect of currently available cancer therapies, alternative therapies are investigated. Studies have shown that mesenchymal stem cells (MSCs) may have a therapeutic potential in glioma treatment. READ MORE

  6. 5. Cloning, Expression and Purification of a Mutant Tomato Thymidine Kinase 1 for Crystallography

    University essay from Lunds universitet/Tillämpad biokemi

    Author : Mohamad Nesrini; [2015]
    Keywords : protein expression; protein engineering; Azidothymidine; thymidine kinase; deoxyribonucleoside kinases; nucleosides; nucleoside analog; suicide gene therapy; tillämpad biokemi; applied biochemistry; BEVS.; Technology and Engineering; Chemistry;

    Abstract : Thymidine kinase 1 from tomato (ToTK1) is a newly discovered deoxyribonucleoside kinase (dNK) that has been subject to study due to its in vitro and in vivo properties making it an interesting suicide gene candidate for the treatment of brain tumors. The ToTK1 phosphorylates the nucleoside analogue 3-azido-2,3-dideoxythymidine (azidothymidine, AZT) equally well as its natural substrate thymidine (dThd). READ MORE