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Showing result 1 - 5 of 7 essays matching the above criteria.

  1. 1. Metagenomic analysis of Crohn’s Disease

    University essay from Uppsala universitet/Molekylär epidemiologi

    Author : Gustav Lennemyr Ahlström; [2022]
    Keywords : Metagenomics; Machine Learning; Microbiome; IBD; Human Health; AI; Crohn s Disease; Shotgun Sequencing Data; Data Analysis; Bioinformatics; MetaPhlAn3; Supervised ML; Mikrobiom; Crohn s Sjukdom; Bioinformatik;

    Abstract : Inflammatory Bowel Disease (IBD) is a chronic and incurable condition that is increasing inprevalence across the globe. This illness consist of two forms: Crohn’s Disease (CD) andUlcerative Colitis (UC). CD is characterised by a patch inflammation pattern across the gut anda multitude of different factors, such as diet. READ MORE

  3. 2. Exercise and the microbiome : Health effects of exercise on gut microbiome modulation in healthy, prediabetic, and diabetic cohorts

    University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Author : Linnea Brengesjö; [2021]
    Keywords : Microbiome; microbiota; gastrointestinal; exercise; diabetes; prediabetes; metabolites; SCFA; inflammation; Mikrobiom; mikrobiota; tarm; träning; diabetes; prediabetes; metaboliter; kortkedjiga fettsyror; inflammation;

    Abstract : Diabetes has caused many deaths worldwide but can be combated at least partially by diet and physical activity. The gut microbiome shows correlation with both type 1 and type 2 diabetes, has modulatory effects on the immune system and implicates brain functions through the gut-brain axis, in part by microbial metabolites. READ MORE

  4. 3. Detection of Sparse and Weak Effects in High-Dimensional Supervised Learning Problems, Applied to Human Microbiome Data

    University essay from KTH/Matematisk statistik

    Author : Fred Lindahl; [2020]
    Keywords : Signal detection; signal identification; higher criticism; microbiome data; sparse and weak effects; goodness-of-fit tests; kolmogorov-smirnov tests; Signal detektering; signal identifiering; higher criticism; mikrobiom data; glesa och svaga effekter; goodness-of-fit tester; Kolmogorov-smirnov tester;

    Abstract : This project studies the signal detection and identification problem in high-dimensional noisy data and the possibility of using it on microbiome data. An extensive simulation study was performed on generated data using as well as a microbiome dataset collected on patients with Parkinson's disease, using Donoho and Jin's Higher criticism, Jager and Wellner's phi-divergence-based goodness-of-fit-test and Stepanova and Pavlenko's CsCsHM statistic . READ MORE

  5. 4. Hundens mikrobiom efter antibiotikabehandling

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Adam Maccormack; [2019]
    Keywords : mikrobiom; mikrobiota; tarmbakterier; hund; antibiotikabehandling; antibiotikaresistens;

    Abstract : Hundens intestinala mikrobiom är ett komplext samspel av organismer med många viktiga funktioner som är essentiella för djurets välmående på en systemisk nivå. Användning av antibiotika är vanlig vid bakteriella infektioner, men vi vet lite om hur antibiotika påverkar hundens mikrobiom på lång sikt och vad följden av potentiella störningar i mikrobiomet skulle kunna vara. READ MORE

  6. 5. Dysbios av hudens mikrobiom vid atopisk dermatit hos hund

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Johanna Onselius; [2019]
    Keywords : atopisk dermatit; hund; dysbios; staphylococcus;

    Abstract : Atopisk dermatit är en vanlig hudsjukdom som drabbar runt 10-15% av alla hundar. Sjukdomen innebär överkänslighetsreaktioner med bland annat klåda mot specifika allergener. Ofta är det allergener som hunden kan komma i kontakt med i vardagen, som till exempel pollen eller husdamm. READ MORE