Essays about: "molecular biology systems"

Showing result 1 - 5 of 28 essays containing the words molecular biology systems.

  1. 1. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    University essay from KTH/Tillämpad fysik

    Author : Samuel Eriksson Lidbrink; [2023]
    Keywords : AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Abstract : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. READ MORE

  3. 2. Computational modelling of photosynthetic excitons coupled to a microcavity

    University essay from Lunds universitet/Fysiska institutionen; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Author : Ilmari Turunen; [2022]
    Keywords : Cavity QED; LH2; Chlorophyll; Exciton; Polariton; Transition dipole moment; Absorbance; Physics and Astronomy; Chemistry; Biology and Life Sciences;

    Abstract : Cavity quantum electrodynamics (QED) is a theory that is used for describing the interaction between matter and cavity modes. Not until relatively recently, cavity QED has been extended to the study of photosynthetic light-harvesting complexes (LHCs). READ MORE

  4. 3. Evaluation of strategies for construction of protease libraries in yeast.

    University essay from Lunds universitet/Teknisk mikrobiologi; Lunds universitet/Bioteknik

    Author : Sidharth Jaya Sankar; [2022]
    Keywords : Yeast; GFP-fusion technology; protease; applied microbiology; Technology and Engineering;

    Abstract : Proteases are a group of enzymes that are involved in breaking down larger proteins into smaller polypeptides or single amino acids, and they are used in various applications. In this project, the potential of budding yeast Saccharomyces cerevisiae as host for the construction of protease libraries is evaluated. READ MORE

  5. 4. Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Fredrik Bertilsson; [2022]
    Keywords : Biophysics; systems biology; gene regulatory networks; neural tube; isthmic organizer; midbrain-hindbrain boundary; WNT; FGF; morphogens; reaction-diffusion; finite-difference; 3D modelling; Physics and Astronomy;

    Abstract : Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. READ MORE

  6. 5. Expression of FLAG-tagged argonautes in Dictyostelium discoideum

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för cell- och molekylärbiologi

    Author : Zozek Abdul Rahman; [2022]
    Keywords : Dictyostelium; discoideum; Argonaute; Protein; FLAG; FLAG-tag; Molecular Biology; Microbiology; SorMC; agnA; agnC; agnE; electrophoresis; pDM304;

    Abstract : Argonautes are conserved RNA-binding proteins that can regulate gene expression post transcriptionally through a process known as RNA interference (RNAi). This is done through the use of small RNAs, e.g. sRNAs that act as a guide for the argonautes, allowing for sequence-specific binding to the target site. READ MORE