Essays about: "monoclonal"
Showing result 1 - 5 of 61 essays containing the word monoclonal.
-
1. OPTIMIZATION OF CLONE SELECTION PLATFORM FOR PRODUCTION OF RECOMBINANT PROTEINS
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : Background Biologics are type of proteins that can be produced by expression in a foreign host for medical healthcare applications in humans. Monoclonal antibodies (mAbs) are type of biologics that are designed to specifically bind to one target, with a purpose to inhibit a certain molecule that could be associated with a disease process. READ MORE
-
2. Establishment and Characterisation of new Immunoreagents for diagnosis of Ovarian cancer
University essay fromAbstract : Ovarian cancer is the most lethal of all gynaecological cancers and it is often diagnosedat an advanced stage due to diffuse and only mild symptoms at early stages.Early detection is crucial to increase survival but high-grade serous ovarian cancer(HGSOC) often presents non-specific symptoms, such as loss of appetite, bloating ofabdomen and tiredness. READ MORE
-
3. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants
University essay from Uppsala universitet/Institutionen för farmaciAbstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE
-
4. Generation of a new ADAPT library for stability improvement
University essay from KTH/ProteinvetenskapAbstract : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. READ MORE
-
5. Implementation of an automatic tangential flow filtration system for latex immunoassay production
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : To diagnose patients suffering from blood clotting disorders latex immununoassays (LIA) can be used. A time consuming manual tangential flow filtration (TFF) process suggests the implementation of an automatic TFF system to improve the efficiency, profitability, and expandability of the production facility of LIA at Nordic Biomarker. READ MORE