Essays about: "mtt assay"

Showing result 1 - 5 of 7 essays containing the words mtt assay.

  1. 1. Studies of broad-spectrum inhibitors against main protease of SARS-CoV-2 and other Coronaviruses

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Alexandra Stanciu; [2023]
    Keywords : human coronavirus 229E; SARS-CoV-2; main protease; nirmatrelvir; GC-376; compound 19;

    Abstract : Coronaviruses have caused three large outbreaks in the past century. The most recent one, also still ongoing, is represented by the SARS-CoV-2/Covid-19 pandemic. Efforts have been taken to develop efficient vaccines and antivirals and one of the major virus-based targets in drug development is represented by the main protease of these viruses. READ MORE

  3. 2. Effects of skin care ingredients on keratinocytes : - Interplay between osmotic stress, cell viability, and gene expression towards increased understanding of keratinocyte differentiation

    University essay from Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Author : Kassem Awad; [2021]
    Keywords : Cell viability; Keratinocytes; Osmotic stress; qPCR; Skin; Water activity;

    Abstract : The epidermis is composed of multiple cell strata where viable keratinocytes, in the basal layer (stratum basale (SB)), go through a range of steps with the final stage of being dead corneocytes in the outer most layer (stratum corneum (SC)). The differentiation, which can be thought of as programmed cell death, include several key processes that are essential for an intact skin barrier. READ MORE

  4. 3. Ouabain Toxicity -Selectivity Towards Renal Cancer Cells

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Emma Magnusson; [2020]
    Keywords : Cardiotonic steroids; ouabain; Na K -ATPase; cytotoxicity; renal cancer; apoptosis; Kardiotoniska steroider; ouabain; Na K -ATPase; cytotoxicitet; njurcancer; apoptos;

    Abstract : Ouabain and other cardiotonic steroids are known to inhibit Na + ,K + -ATPase (NKA), theion pump responsible for the ionic gradient across the plasma membrane. These steroidsdisplay a selective toxicity towards several tumour cells in comparison to primary humancells, however, the mechanism behind this is not yet understood. READ MORE

  5. 4. Protective capabilities of allopregnanolone against induced toxicity in SH-SY5Y cells relative to Alzheimer´s disease.

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Mohamed Mustafa; [2020]
    Keywords : allopregnanolone; neurosteroid; alzheimer s disease; SH-SY5Y; neuroprotection;

    Abstract : When the brain is exposed to a traumatic injury, the brain produces high amounts of neurosteroids like allopregnanolone and progesterone which show protective and neurogenic capacities. Alzheimer’s disease patients also have lower amounts of these neurosteroids in brain tissue. READ MORE

  6. 5. Toxicological effects of food additives azo dyes

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Cristina Gil; [2014]
    Keywords : endocrine disruptor; Human adrenocortical H295R ; cell line; azo dyes; MTT assay;

    Abstract : BACKGROUND: Azo dyes are widely used in foods, pharmaceuticals and cosmetics. They have been tested in several screenings regarding their effects on human health, but very little data is available on endocrine disrupting effects. READ MORE