Essays about: "neuroprotection"

Found 5 essays containing the word neuroprotection.

1. 1. Promote neuroprotection and axonal outgrowth in the central and peripheral neural system

   University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

   Author : Elin Petersson; [2021]
   Keywords : Spinal cord injury; interleukin-1 receptor antagonist; excitotoxicity; qPCR; dorsal root ganglion.;

   Abstract : Acute spinal cord injury is often caused by collisions with motor vehicles, falls or violence. This injury could potentially lead to paraplegia or tetraplegia, causing great economic and personal loss. The patophysiology is biphasic, with primary and secondary mechanisms. READ MORE

3. 2. Neuroprotective effects of magnesium sulphate evaluated by fluoride resistant acid phosphatase, inorganic phosphate, lactate dehydrogenase and nitric oxide in rats with ischemia

   University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

   Author : Maria Dorelis Montero Jimenez; [2020]
   Keywords : Biomarker; Magnesium; Neuroprotection; Respiratory arrest.;

   Abstract : Brain ischemia events are among the first three mortalities causes in the world associated with high treatments costs and in most cases some degree of permanent functional disability, thus it is necessary with new low cost and effective treatments. In the present study the potential neuroprotective effect of magnesium sulphate was evaluated by quantification of ischemic biomarkers: fluoride resistant acid phosphatase (FRAP), inorganic phosphate (Pi), lactate dehydrogenase (LDH) and nitric oxide (NO) in rats with global ischemia. READ MORE

4. 3. Protective capabilities of allopregnanolone against induced toxicity in SH-SY5Y cells relative to Alzheimer´s disease.

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Mohamed Mustafa; [2020]
   Keywords : allopregnanolone; neurosteroid; alzheimer s disease; SH-SY5Y; neuroprotection;

   Abstract : When the brain is exposed to a traumatic injury, the brain produces high amounts of neurosteroids like allopregnanolone and progesterone which show protective and neurogenic capacities. Alzheimer’s disease patients also have lower amounts of these neurosteroids in brain tissue. READ MORE

5. 4. Towards Identifying Pharmacodynamic Blood Biomarkers of MAP3K12 Inhibition

   University essay from Lunds universitet/Tillämpad biokemi

   Author : Elisabeth Jirström; [2017]
   Keywords : Mitogen-activated protein kinase kinase kinase; MAP3K12; Amyotrophic lateral sclerosis; DLK; ALS; Pharmacodynamic; Biomarker; applied biochemistry; tillämpad biokemi; Technology and Engineering; Biology and Life Sciences; Medicine and Health Sciences; Chemistry;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons in the brain and spinal cord, for which there is no cure. Activation of the stress-induced c-Jun N-terminal kinase (JNK) signaling pathway, a critical mediator of neuronal apoptosis and axon degeneration, is evident in ALS and is therefore considered a potential target to prevent neurodegeneration. READ MORE

6. 5. Effect of GLP-1R Knockout on stroke outcome

   University essay from KTH/Skolan för teknik och hälsa (STH)

   Author : Alexandra Voinea; [2014]
   Keywords : Technology;

   Abstract : Stroke is the leading cause of disability in adults in westernized societies and it has an important impact on health and economy. Comorbid health conditions such as hypertension, inactive lifestyle, smoking, obesity and diabetes considerably increase the risk of stroke. READ MORE