Essays about: "next generation sequencing NGS"

Showing result 1 - 5 of 15 essays containing the words next generation sequencing NGS.

  1. 1. Coverage Analysis in Clinical Next-Generation Sequencing

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Anna Odelgard; [2019]
    Keywords : ;

    Abstract : With the new way of sequencing by NGS new tools had to be developed to be able to work with new data formats and to handle the larger data sizes compared to the previous techniques but also to check the accuracy of the data. Coverage analysis is one important quality control for NGS data, the coverage indicates how many times each base pair has been sequenced and thus how trustworthy each base call is. READ MORE

  2. 2. Evaluation of next-generation sequencing as a tool for determining the presence of pathogens in clinical samples

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Alexander Kokkonen; [2019]
    Keywords : NGS; next generation sequencing; clinical microbiology; systems biology;

    Abstract : Metagenomic sequencing is an increasingly popular way of determining microbial diversity from environmental and clinical samples. By specifically targeting the 16S rRNA gene found in all bacteria, classifications of pathogens can be determined based on the variable and conserved regions found in the gene. READ MORE

  3. 3. Sepsis : Genotypic analysis of clinical Klebsiella spp. using next-generation sequencing

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Patricia Saxenborn; [2018]
    Keywords : Sepsis; Klebsiella; systems biology; next-generation sequencing; NGS;

    Abstract : Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response system and can occur when the immune system over- or under- reacts to an infection. Klebsiella spp. READ MORE

  4. 4. Investigating streptococcal biodiversity in sepsis using next-generation sequencing

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Daniel Shahbazi; [2018]
    Keywords : sepsis; streptococci; NGS; next-generation sequencing; pathogenfinder; plasmidfinder; speciesfinder; SPAdes; QUAST;

    Abstract : Sepsis is one of the leading causes for fatalities in the intensive care unit, and also one of the biggest health problems worldwide. It is a disease caused primarily by bacterial infections but can also be caused by viral or fungal infections. READ MORE

  5. 5. Haplotype Inference as a caseof Maximum Satisfiability : A strategy for identifying multi-individualinversion points in computational phasing

    University essay from Uppsala universitet/Molekylär evolution

    Author : Ebba Bergman; [2017]
    Keywords : Haplotypes; Maximum Satisfiability; Weighted Maximum Satisfiability; Logic; Bioinformatics; cnF2freq; chaplink;

    Abstract : Phasing genotypes from sequence data is an important step betweendata gathering and downstream analysis in population genetics,disease studies, and multiple other fields. This determination ofthe sequences of markers corresponding to the individualchromosomes can be done on data where the markers are in lowdensity across the chromosome, such as from single nucleotidepolymorphism (SNP) microarrays, or on data with a higher localdensity of markers like in next generation sequencing (NGS). READ MORE