Essays about: "nk"

Showing result 1 - 5 of 33 essays containing the word nk.

  1. 1. Cytokine capture with beads in cytotoxicity assays in microwells

    University essay from KTH/Tillämpad fysik

    Author : Maxime Simon; [2023]
    Keywords : Microbead; Inteferon gamma; Natural Killer cells; microwell; binding-reaction model; Mikrokula; Interferon gamma; Naturliga Mördarceller; Mikrobrunn; modell för bindningsreaktion;

    Abstract : Cytokines are small, secreted proteins that are important for cell signalling in theimmune system. Interferon gamma (IFN-γ) is one of the most potent cytokines thatnatural killer (NK) cells of the innate immune system secrete with both antiviral,antibacterial, and antitumoral activity. READ MORE

  3. 2. Single-molecule Imaging of the Cell Division Ring in Escherichia coli Using the ALFA-tag

    University essay from KTH/Tillämpad fysik

    Author : Emma Westlund; [2023]
    Keywords : ALFA-tag; Escherichia coli; Divisome protein FtsZ; mEos3.2; Nanobodies; Nanotags; PALM; Plasmid transformation; sfGFP; Single-molecule Imaging; ALFA-tag; Escherichia coli; Divisomprotein FtsZ; mEos3.2; Nanokroppar; Nanotaggar; PALM; Plasmidtransformation; sfGFP; Enmolekyl-mikroskopi;

    Abstract : The use of super-resolution (SR) microscopy is an important tool for understanding the inside mechanisms of bacterial cells. However, for SR imaging, the labelling of the proteins of interest is a great challenge as flourescent proteins (FPs) are often too big to be directly fused to the target protein and traditional immunolabelling with antibodies creates too long separation between the fluorophore and the target protein. READ MORE

  4. 3. Feedback imaging of cellular dynamics with fluorescence microscopy

    University essay from KTH/Tillämpad fysik

    Author : Emil Sorcini; [2022]
    Keywords : Tracking; Segmentation; Fluorescence microscopy; Lattice light-sheet; Cell migration; NK cells; ZEN; OAD; Experiment Feedback; Spårning; Segmentering; Fluorescensmikroskopi; Lattice light-sheet; Cellmigration; NK celler; ZEN; OAD; Experiment Feedback;

    Abstract : In biology, it is common to study cultured cells (in vitro) with fluorescence time-lapse microscopy. The cells are recorded for longer period of time and can later be viewed at an accelerated speed. During the acquisition some live cells tend to migrate. READ MORE

  5. 4. Structural features underlying antigen presentation by the non-classical MHC class Ib molecule Qa-1b

    University essay from KTH/Proteinvetenskap

    Author : Lejla AI-Tamimi; [2022]
    Keywords : immune checkpoint; NKG2A; MHC class Ib; Qdm; antibody; crystal structure;

    Abstract : Blockering av NKG2A receptorn på NK - och CD8+ T celler med en anti-NKG2A antikropp, medför en aktivering av cytolytisk aktivitet, och är en lovande immunkontrollpunkt i immunterapi mot cancer. Nyligen har en TCR-liknande antikropp, EXX1, som binder till liganden för NKG2A receptorn, Qa-1b - en icke-klassisk MHC klass Ib molekyl i möss -studerats i tumör modeller in vitro. READ MORE

  6. 5. Utilizing cytotoxic lymphocytes for indirect shock-and-kill strategy in HIV-1 treatment

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Joana FIlipa Furtado Milão; [2021]
    Keywords : HIV-1; Shock-and-kill strategy; NK cells; latency reservoir; HIV-1 treatment;

    Abstract : Despite the existence of a treatment, there is still not a cure for HIV-1 infection and there arearound 700 000 deaths per year from AIDS-related diseases. A major barrier for a cure is theestablishment of latent reservoirs that are impossible to distinguish from healthy cells and thuscan escape the immune system. READ MORE