Essays about: "non-coding regions"

Showing result 6 - 10 of 12 essays containing the words non-coding regions.

  1. 6. Analysis of differentially expressed genes (DEGs) in neuronal cells from the cerebral cortex of Alzheimer’s disease mouse model

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Elnaz Bakhtiyari; [2020]
    Keywords : ;

    Abstract : Alzheimer’s disease (AD) is an aging-related neurodegenerative disorder with large implications for society and individuals. AD is a multi-factor disorder, with these factors having a direct or indirect correlation with each other. READ MORE

  3. 7. A zebrafish-based system to study the impact of environmental factors in Inflammatory Bowel Disease (IBD)

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Mikaela Westling; [2020]
    Keywords : IBD; non-coding regions; zebrafish; in vivo; transgenic dual reporters; enhancer activity; polyfluoroalkyl substances; dietary sensors;

    Abstract : Inflammatory Bowel Disease (IBD) is a chronic disorder that affects millions of peopleworldwide. Although the etiology behind the disease is yet unknown, current theoriespropose a complex interplay between genetic susceptibility, exposure to environmentalfactors and exacerbated immune responses. READ MORE

  4. 8. Identification of DEGs in B cells of patients with common variable immunodeficiency and healthy donors

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Shirin Pour Akaber; [2019]
    Keywords : ;

    Abstract : Common variable immunodeficiency (CVID) is a rare primary immune deficiency (1:25000) in which patients have a reduction in antibody production and very low titres in one or more of their Ig isotypes, (IgG, IgA and sometimes IgM). This disease can cause different symptoms such as: bronchiectasis, chronic lung disease and even autoimmunity, polyclonal lymphocytic infiltration, lymphoma and death. READ MORE

  5. 9. Unsupervised hidden Markov model for automatic analysis of expressed sequence tags

    University essay from Bioinformatik

    Author : Andrei Alexsson; [2011]
    Keywords : Machine learning; Markov Model; Hidden Markov Model; Expressed sequence tag; EST; Baum-Welch; 1-best; Unsupervised; Supervised; GHMM;

    Abstract : This thesis provides an in-depth analyze of expressed sequence tags (EST) that represent pieces of eukaryotic mRNA by using unsupervised hidden Markov model (HMM). ESTs are short nucleotide sequences that are used primarily for rapid identificationof new genes with potential coding regions (CDS). READ MORE

  6. 10. Bioinformatics analysis of ZBED6, a novel transcription factor in mammals

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Shumaila Sayyab; [2010]
    Keywords : Chromatin Immuno precipitation ChIP sequencing; non-coding RNA; transcription factor; overrepresentation; enhancer elements; co regulation; repressor;

    Abstract : The identification of a regulatory mutation in the intron 3 of Insulin like growth factor 2, was a major finding. This single nucleotide mutation in the non coding region abrogates the interaction of nuclear factor ZBED6, resulting in the 3-4% increase in the muscle mass of domesticated pigs. READ MORE