Essays about: "oligomers"

Showing result 1 - 5 of 20 essays containing the word oligomers.

1. 1. Different concentrations of GSK3 inhibitor fail to suppress interleukin-6 in stimulated THP-1 macrophage

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Batoul Shunnar; [2022]
   Keywords : ;

   Abstract : Inflammation is a defensive process that allows immune cells to be mobilized to help with infection removal and tissue regeneration. Inflammasomes are multiprotein oligomers in the cytoplasm and components of the innate immune system that have a role in inflammation. READ MORE

3. 2. Expression & affinity analysis of recombinant RX against pathogenic α-synuclein

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Isak Simon; [2021]
   Keywords : Parkinson’s disease; α-synuclein; ELISA; Biological drugs; Protein-based drugs;

   Abstract : Background In the as of yet uncurable Parkinson´s disease aggregation of α-syn is an accelerator of pathogenesis. Oligomers of α-synuclein is considered to be neurotoxic hence blocking the endocytosis of aggregated α-syn is possibly a way of preventing pathogenesis. READ MORE

4. 3. BICONTINUOUS MACROPOROUS MATERIALS FROM EPOXY RESIN-BASED MONOLITHS

   University essay from Umeå universitet/Kemiska institutionen

   Author : Thuy Trân Ho-Thi; [2021]
   Keywords : ;

   Abstract : In this project, hydrophilic bicontinuous microporous materials were synthesized via one‑pot polycondensation, using epoxy compounds and polyamines as the main monomer and curing agents. To achieve this goal, two approaches have been taken. READ MORE

5. 4. The anti-amyloidogenic chaperone DNAJB6 and its interaction with other chaperones

   University essay from Lunds universitet/Matematisk statistik; Lunds universitet/Kemiska institutionen

   Author : Gemma Nilsson; [2020]
   Keywords : chaperones; DNAJB6; Hsc70; Hsp110; ATP-hydrolysis; Ab42; polyQ; biochemistry; biokemi; Chemistry;

   Abstract : In order to maintain proteins’ functionality their native folding state must be preserved. Chaperones fold other proteins and DNAJ-chaperones may collaborate with Hsc70 chaperones to prevent aggregation of aggregation-prone peptides such as polyQ and Aβ42, which form fibrils in currently incurable diseases as Huntington’s and Alzheimer’s, respectively. READ MORE

6. 5. PREPARATION AND CHARACTERIZATION OF BOVINE MEAT AND MILK FACTOR VESICLES/PARTICLES & IDENTIFICATION OF MSBI1 REP INTERACTING PROTEINS

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Farhana Manzoor; [2020]
   Keywords : Bovine meat and milk factors; multiple sclerosis; immunoprecipitation co-immunoprecipitation; protein dimers; mass spectrometry; immunodetection; cesium chloride density gradient centrifugation; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; vesicle; particle; interaction partner; pull-down assay.;

   Abstract : Introduction: Bovine meat and milk factors (BMMF) frequently isolated from bovine meat and milk, are discussed as putative causative agents for breast, colon and possibly other cancers. The hypothesis was formulated based on earlier correlative studies indicating that BMMFs could indirectly trigger inflammation, accumulate mutational events via reactive oxygen and nitrogen species production which eventually provokes tumor formation. READ MORE