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Showing result 1 - 5 of 24 essays matching the above criteria.

1. 1. A novel assay for the detection of Hepatitis C virus in blood plasma, using padlock probes and rolling circle amplification

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Andréa Karlsson; [2023]
   Keywords : ;

   Abstract : Hepatitis C viral infection is a globally widespread blood-borne disease affecting the liver, causing cirrhosis and hepatocellular carcinoma. This type of liver cancer is mainly caused by chronic Hepatitis C and Hepatitis B. Specific detection with the following correct treatment is crucial to reduce the overall burden of the disease. READ MORE

3. 2. Methodological development of human telomere sequencing with the Oxford Nanopore Technologies

   University essay from Örebro universitet/Institutionen för hälsovetenskaper

   Author : Jennifer Arnqvist; [2023]
   Keywords : ;

   Abstract : Human DNA is protected with telomeres, which consist of the repetitive DNA-sequence TTAGGG. A 3’-overhang folds back and in combination with the shelterin complex protects the ends of the DNA. READ MORE

4. 3. Ion pair chromatography of carboxylic and sulfonic acids with trialkylamines : An investigation of the relationship between the adsorption isotherm of the IPR and the retention factor of the analyte

   University essay from Karlstads universitet/Institutionen för ingenjörs- och kemivetenskaper (from 2013)

   Author : Karl Kullberg; [2023]
   Keywords : ;

   Abstract : Ion pair chromatography has found many uses within analytical chemistry and understanding of the chromatographic process with an ion-pairing reagent have been studied since the 1970s. The adsorption of the Ion-pairing reagent to the stationary phase is understood to be important and many studies have been dedicated to looking at the adsorption isotherms of the earlier quaternary alkylammonium ions. READ MORE

5. 4. PAMPaR: Parallel Analysis of miRNAs, Proteins and RNAs. Dynamic Profiles of miRNAs, mRNAs and Specific Proteins in Mouse Embryonic Stem Cells Differentiating into Neural Precursors

   University essay from KTH/Proteinvetenskap

   Author : Amelie Carlström; [2023]
   Keywords : PAMPaR; SPARC; Proximity extension assay; Neuronal differentiation; Mouse embryonic stem cells; PAMPaR; SPARC; Proximity extension assay; Neuronal differentiering; embryonala musstamceller;

   Abstract : MikroRNA-molekyler (miRNA) är viktiga icke-kodande RNA-molekyler för post-transkriptionell reglering av proteinkodande gener. De har även effekter på många cellulära processer såsom differentiering. De biosyntetiska reaktioner som skapar miRNA involverar proteiner som själva regleras av miRNA. READ MORE

6. 5. The Synthesis and Development of Potential Small Molecule Splice Modifiers toward a central nervous system (CNS) target for the treatment of a genetic disease

   University essay from KTH/Kemiteknik

   Author : Flore Miomandre; [2023]
   Keywords : organic synthesis; medicinal chemistry; pharmaceutical candidate; small molecule; genetic disease; organisk syntes; läkemedelskemi; läkemedelskandidat; småmolekylär; genetisk sjukdom;

   Abstract : Behandling av sällsynta sjukdomar är en stående utmaning inom läkemedelskemi då mer än 400 miljoner människor lider av 7000 olika sällsynta sjukdomar där få godkända läkemedel finns tillgängliga. Fokus för detta arbete är att syntetisera läkemedelskandidater för en sällsynt och livslång form av epilepsi med frekventa och långvariga anfall. READ MORE