Essays about: "peptides"

Showing result 1 - 5 of 114 essays containing the word peptides.

  1. 1. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sara Forsberg; [2023]
    Keywords : High-throughput analysis; Impurity profiling; UHPLC-HRMS; Peptide characterization; Peptide descriptors; Analytical chemistry; Technology and Engineering;

    Abstract : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. READ MORE

  3. 2. Understanding the effects of TCP-25 and EDTA interaction : A study of the biophysical aspects of a naturally derived peptide formulation with EDTA for topical application

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Ebba Kant; [2023]
    Keywords : chronic wounds; EDTA; biophysical aspects; formulation; pharmaceutical technology; Thrombin derived C-terminal peptide; Technology and Engineering;

    Abstract : Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improving wound healing. READ MORE

  4. 3. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design

    University essay from Uppsala universitet/Beräkningsbiologi och bioinformatik

    Author : Linde Brokmar; [2023]
    Keywords : Protein design; de novo design; protein engineering; generative ai; machine learning; peptide binders; AF2; EvoBind; RFdiffusion; ProteinMPNN;

    Abstract : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. READ MORE

  5. 4. Sustainable utilization of waste and by-products from the meat industry

    University essay from SLU/Department of Molecular Sciences

    Author : Anton Glimåker; [2023]
    Keywords : Food waste; sustainability; protein; bioactive peptides; enzymes;

    Abstract : The purpose of this research was to summarise existing scientific literature on waste and by-products from the meat industry and suggest how the meat industry can use it in order to reduce environmental damage, increase food availability and contribute to the achievement of the Sustainable Development Goals. The report is a literature study were several databases were used. READ MORE

  6. 5. Structural and Functional Characterisation of the Human Mitochondrial Pyruvate Carrier

    University essay from Lunds universitet/Kemiska institutionen

    Author : Simon Gripvall; [2023]
    Keywords : biochemistry; complex; MPC; proteoliposomes; pyruvate; transport; Chemistry;

    Abstract : The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases. READ MORE