Essays about: "phage"

Showing result 1 - 5 of 33 essays containing the word phage.

  1. 1. Generation of a new ADAPT library for stability improvement

    University essay from KTH/Proteinvetenskap

    Author : Sumant Yogesh Salphale; [2023]
    Keywords : Phage display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; protein engineering; cancer detection; Fag-display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; proteinteknik; cancerdetektion;

    Abstract : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. READ MORE

  3. 2. Evaluation of antimycobacterial molecules' capacity to kill mycobacteria and their toxic effect on human cells.

    University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Author : Filippa Henriksson; [2023]
    Keywords : Drug evaluation; In vitro; Mycobacterium tuberculosis complex; REMA; Tuberculosis; In vitro; Mycobacterium tuberculosis complex; REMA; tuberkulos; utvärdering av läkemedel;

    Abstract : Tuberculosis is a fatal airborne disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). The incidence of contracting tuberculosis is estimated to be around 10.6 million cases each year. Increased drug resistance among mycobacteria has led to the need to develop new treatments. READ MORE

  4. 3. Pipeline for Next Generation Sequencing data of phage displayed libraries to support affinity ligand discovery

    University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Author : Ella Schleimann-Jensen; [2022]
    Keywords : NGS; next generation sequencing; phage display; affinity ligands; data analysis; bioinformatics;

    Abstract : Affinity ligands are important molecules used in affinity chromatography for purification of significant substances from complex mixtures. To find affinity ligands specific to important target molecules could be a challenging process. Cytiva uses the powerful phage display technique to find new promising affinity ligands. READ MORE

  5. 4. Affibody phage display selections for lipid nanoparticle and affibody-mediated transient CAR T-cell therapy

    University essay from KTH/Proteinvetenskap

    Author : Tasnim Yasin Idris; [2022]
    Keywords : affibody; phage display; in vitro selection; CD5; CD8; CD19; CAR T-cell therapy.;

    Abstract : CAR T-cellbehandling är en immunterapi som har visat lovande resultat vid behandling av cancer. Trots det riktade immunsvaret som kan uppnås, betonar komplexiteten i tillverkningsprocessen och behandlingsproceduren det utrymme somm finns för förbättringar. READ MORE

  6. 5. Towards an understanding of the Retraction of TYPE IV PILI as a Mechanoresponse upon surface contact in Pseudomonas Aeruginosa

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Antoine Loussouarn; [2022]
    Keywords : Mechanosensing; Microscopy; Bacteria; Microfabrication; Genetics; Molecular Biology; Biophysics;

    Abstract : Pseudomonas Aeruginosa is an opportunistic bacterium which is involved in nosocomial infections and which causes increasing concern in healthcare due to its high antibiotic resistance. During an infection by P.aeruginosa, the bacteria proliferate in the host’s organism by leveraging motility abilities. READ MORE