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Showing result 1 - 5 of 48 essays matching the above criteria.
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1. Metabolic Crisis Induced by Antiepileptic Drugs in Patients with Mitochondrial Epilepsy : The Effect of Valproic Acid, Topiramate and Propofol on Mitochondrial Function
University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)Abstract : Mitochondria are important cytosolic organelles present in nearly all eukaryotic cells. The main function of mitochondria are to generate the vast majority of ATP through the process of oxidative phosphorylation. READ MORE
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2. Effects of phosphorylation on the ADP-ribosylation activity of PARP16
University essay from Lunds universitet/Kemiska institutionenAbstract : PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. READ MORE
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3. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma
University essay from KTH/ProteinvetenskapAbstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE
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4. Ligand-stimulated cleavage of PDGFR-beta
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. READ MORE
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5. Serum TK1 activity and SAA concentration as biomarkers to differentiate lymphoma from gastrointestinal disease in cats
University essay from SLU/Dept. of Clinical SciencesAbstract : Alimentary lymphoma is one of the most common malignant neoplasms in the gastrointestinal (GI) tract in cats. Since the clinical signs often are identical to those of inflammatory bowel disease (IBD), and the findings on diagnostic imaging and endoscopic mucosal biopsies overlap, invasive biopsy sampling from the GI tract is needed to be able to differentiate these two diseases from each other. READ MORE