Essays about: "proteasome inhibition"

Found 3 essays containing the words proteasome inhibition.

  1. 1. Regulation of Ski co-repressor stability by TGF-β signaling in normal and tumorigenic hepatocytes

    University essay from Institutionen för vård och natur

    Author : Carolin Dinha; [2011]
    Keywords : ;

    Abstract : Transforming growth factor beta (TGF-β) is a multifunctional cytokine that regulates cell differentiation, proliferation and migration depending on cell context. TGF-β has a growth inhibitory effect on epithelial cells via activation of Smad proteins (R-Smad/Co-Smad complex). READ MORE

  3. 2. Algorithmic analysis of drug induced apoptosis and proteasome inhibition in cancer cells based on time-lapse microscopy images

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Aftab Obaid; [2010]
    Keywords : Time-lapse microscopy; apoptosis; proteasome inhibition; CellProfiler;

    Abstract : Time lapse microscopy imaging has revolutionized the study of dynamic events taking place inside living cells. When combined with automated image analysis it provides a powerful tool that enables spatiotemporal large-scale quantification at the level of complete cell population. READ MORE

  4. 3. Algorithms offering kinetic analysis of drug induced proteasome inhibition and cell clump formation from time lapsed microscopy

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Mohammad Kashif; [2010]
    Keywords : Image processing; time lapsed microscopy; kinetic studies; cell clumps; proteasome inhibition;

    Abstract : High content screening (HCS) has potential to transform many biological fields, ranging from drug discovery to gene function discovery. HCS with time lapsed microscopy provide valuable insight information about live cells experiments that are usually lost during manual end point experiments. READ MORE