Essays about: "protein-based pharmaceutical"
Showing result 1 - 5 of 7 essays containing the words protein-based pharmaceutical.
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1. Effects of mixed surfactant system on chemical and physical stability of human growth hormone
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : In protein formulation, addition of surfactants is commonly executed to enhance product stability and shelf-life. The reason is that surfactants can protect proteins against surface-induced aggregation. However, the interaction between surfactant and protein depends on the type of surfactant used. READ MORE
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2. Methods to study device induced aggregation of proteins
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : This work developed a method for the investigation of how medical devices, such as syringes and needles, affect the formation of subvisible particles in a protein drug without excipients. Protein-based pharmaceuticals are well known to be sensitive to different kinds of stress, and exposure to stress during the use of this device is unavoidable. READ MORE
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3. Study of surfactant-preservative and protein-preservative interactions in multi-dose injectable formulation
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Multidose injectable formulations require a preservative such as phenol to ensure sterility and protection against microbial contamination during clinical use. However, it is known that the interaction between these components and non-ionic surfactants such as polysorbate 80, also found in this type of formulations, present incompatibilities, which can lead to decreases in the efficacy of the product. READ MORE
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4. Phenol-Protein Solution Stability
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Phenol is a commonly used preservative in pharmaceutical protein solutions. It is compatible with most proteins but can cause aggregation and denaturation at higher concentrations or in more sensitive proteins. READ MORE
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5. Effects of pharmaceutical excipients on the chemical stability of therapeutic proteins in a parenteral formulation
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Proteins and peptides are widely used for the prevention, management, and cure of various illnesses. This vast therapeutic potential represents a significant portion of the pharmaceutical industry in the form of vaccines, antibodies, enzymes, and other protein-based therapeutics. READ MORE
