Essays about: "pulmonary drug delivery"

Showing result 1 - 5 of 6 essays containing the words pulmonary drug delivery.

1. 1. DRY POWDER FOR INHALATION - INFLUENCE OF MIXING PROCESS AND ADDITION OF MAGNESIUM STEARATE

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Love Ivarsson; [2023]
   Keywords : inhalation; drug delivery; pulmonary drug delivery; API; FPF; FPD; DD; Turbula; Diosna; mixing energy; mixing time; mixing speed; pharmaceutical technology; Medicine and Health Sciences;

   Abstract : For efficient treatment of many diseases of the lung, it is beneficial to deliver the medicine to the respiratory tract directly. This ensures a rapid response since it can enter the bloodstream directly through the alveolar epithelium. Consequently, also decreases systemic effects due to the local treatment. READ MORE

3. 2. Adhesive mixtures for dry powder inhalation

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Louise Lagercrantz Forss; [2021]
   Keywords : Adhesive mixtures; dry powder inhaler; excipients; pulmonary route; powder mixing;

   Abstract : When it comes to dry powder inhalation (DPI), adhesive mixtures are the most widely used formulation type. Various techniques have been developed to generate inhaled drug particles and improve the delivery efficiency of DPI formulations. READ MORE

4. 3. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Venus Zafranian; [2021]
   Keywords : Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

   Abstract : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. READ MORE

5. 4. Characterization of the effect of the membrane on in vitro dissolution profiles for pulmonary drug delivery

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Maral Simonides; [2021]
   Keywords : Oral inhalation; in vitro dissolution; Budesonide; Fluticasone propionate; Transwell;

   Abstract : It has always been a challenge to imitate the lung environment, therefore there is a constant development of standardized in vitro dissolution methods for inhaled products. Dissolution in vitro has been considered as an important parameter, because low solubility determines the bioavailability of inhaled drugs. READ MORE

6. 5. A Passive Constant Flow Regulator for Drug Delivery to the Human Lung in Portable Inhaler Systems

   University essay from KTH/Medicinteknik och hälsosystem

   Author : Maria Pereverzina; [2020]
   Keywords : Inhalation systems; flow regulator; passive; portable; prototype;

   Abstract : Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), are pathological conditions affecting the airways of the respiratory system. Currently more than 90 million people are suffering from respiratory diseases, and COPD is predicted to become the third leading cause of death in the world by 2030. READ MORE