Essays about: "pyrosequencing"

Showing result 1 - 5 of 9 essays containing the word pyrosequencing.

  1. 1. Impact of BPA, BPF and Mixture N1 on DNA-Methylation of GRIN2B and NR3C1 during human neuroprogenitor cell differentiation

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Fysiologi och miljötoxikologi

    Author : Franziska Sophie Richter; [2023]
    Keywords : Epigenetics; Endocrine disrupting chemicals; DNA methylation; EDCs; Mixture effects; BPA; BPF; Mixture N1;

    Abstract : Endocrine disrupting chemicals (EDCs) are ubiquitous and their adverse impact on nature, wildlife and humans is extensively researched. We are constantly exposed to EDCs, such as the widespread and extensively researched Bisphenol A, as well as its substitute Bisphenol F, which is coming into wider use, even though it is much less is researched and limited information is available about its endocrine effects. READ MORE

  2. 2. Effect of Endocrine Disruptor Chemicals(EDCs) Mixture G1 on Molecular Endpoints in Human Mesenchymal Stem Cells

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Wedyan Azeez Saleh Bahr; [2022]
    Keywords : ;

    Abstract : Endocrine disrupting chemicals (EDCs) are used in many every-day products but they can alter functions of the endocrine system. Exposure to these chemicals during early development can lead to long term health adversities. READ MORE

  3. 3. Genetic variation of ASIP and MC1R in past and present sheep of Gotland

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Kristina Westberg Sunesson; [2015]
    Keywords : aDNA; sequencing; sheep; gammalt DNA; sekvensering; får;

    Abstract : Ovine black coat colour is determined by the MC1R (Melanocortin 1 receptor) and ASIP (Agouti signalling peptide) genes at the Agouti and Extension loci. The black phenotype is caused by production of eumelanin by melanocytes, whereas yellow-tan or light phenotype is the result of phaeomelanin synthesis. READ MORE

  4. 4. Analysis of PIK3CA mutations in tumours from patients with non-small cell lung cancer using pyrosequencing

    University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Author : Jennifer Jonasson; [2014]
    Keywords : PI3K; tumour marker; pseudogene; oncogene; targeted therapy;

    Abstract : A subgroup of non-small cell lung cancer (NSCLC) cases harbour mutations in classical oncogenes, which can affect therapy response and prognosis. By therapeutically targeting the corresponding proteins with inhibitory drugs, the clinical outcome for these lung cancer patients may be improved. READ MORE

  5. 5. Marker generation for Fine Mapping a QTL in the chicken

    University essay from Linköpings universitet/Biologi; Linköpings universitet/Tekniska högskolan

    Author : Ahlgren Elisabeth; [2014]
    Keywords : Behavior; Red Junglefowl; Single Nucleotide Polymorphism marker; Tonic immobility; White Leghorn; QTL analysis;

    Abstract : The purpose of this study was to design and test five SNP markers in an inbred chicken cross between Red Junglefowl and domestic White Leghorn of the 8th generation. The markers lie in a region affecting the tonic immobility behaviour which differs significantly between the two species. READ MORE