Essays about: "quantitative technique"

Showing result 1 - 5 of 232 essays containing the words quantitative technique.

  1. 1. Virtual H&E Staining Using PLS Microscopy and Neural Networks

    University essay from Lunds universitet/Matematik LTH

    Author : Sally Vizins; Hanna Råhnängen; [2024]
    Keywords : Deep learning; Virtual staining; Skin tissue; Hematoxylin Eosin; H E; Pathology; Carcinoma; Point light source illumination; Neural Networks; GANs; Generative adversarial networks; CNNs; Convolutional neural networks; Relativistic generative adversarial network; Unet; Digital microscopy; Attention-Unet; Dense-Unet; Mathematics and Statistics;

    Abstract : Histopathological examination, crucial in diagnosing diseases such as cancer, traditionally relies on time- and resource-consuming, poorly standardized chemical staining for tissue visualization. This thesis presents a novel digital alternative using generative neural networks and a point light source (PLS) microscope to transform unstained skin tissue images into their stained counterparts. READ MORE

  3. 2. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  4. 3. Leveraging CNN for Automated Peak Picking in Untargeted Metabolomics without Parameter Dependencies

    University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

    Author : Vivian Wang; Lidia Yalew; [2023-10-19]
    Keywords : Deep learning; Convolutional neural network; LC-MS; Peak Detection; Metabolomics; Faster R-CNN;

    Abstract : Metabolomics is a scientific discipline that involves the thorough analysis of small molecules, known as metabolites, found within a biological system. Furthermore, liquid chromatography-mass spectrometry (LC-MS) is a commonly used analytical technique in metabolomics for analysing biological samples due to its broad coverage of the measurable metabolome. READ MORE

  5. 4. Method development of flow cytometry analysis of yeast and lactic acid bacteria viability for alcohol fermentation

    University essay from Lunds universitet/Teknisk mikrobiologi; Lunds universitet/Bioteknik

    Author : Megha Komahan; [2023]
    Keywords : Flow cytometry; yeast; lactic acid bacteria; fermentation; cell viability; applied microbiology; Technology and Engineering;

    Abstract : The usage of yeast in conventional brewing techniques involving alcoholic fermentation is an age-old process. Analyzing the viability and obtaining physiological information regarding the microbial diversity of the fermentation samples plays a pivotal role in obtaining real-time information as well as developing a more efficient process design. READ MORE

  6. 5. Towards gradient faithfulness and beyond

    University essay from Högskolan i Halmstad/Akademin för informationsteknologi

    Author : Vincenzo Buono; Isak Åkesson; [2023]
    Keywords : XAI; Visual Explanations; CAM; Grad-CAM; Expected Grad-CAM; Hyper Expected Grad; Class Activation Maps; Explainable AI; Faithfulness; Neural Network interpretability; Hyper Resolution CAM; Super Resolution CAM; Natural Encoding;

    Abstract : The riveting interplay of industrialization, informalization, and exponential technological growth of recent years has shifted the attention from classical machine learning techniques to more sophisticated deep learning approaches; yet its intrinsic black-box nature has been impeding its widespread adoption in transparency-critical operations. In this rapidly evolving landscape, where the symbiotic relationship between research and practical applications has never been more interwoven, the contribution of this paper is twofold: advancing gradient faithfulness of CAM methods and exploring new frontiers beyond it. READ MORE