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Found 2 essays matching the above criteria.

1. 1. Greening peptide chemistry by using NBP as solvent for SPPS

   University essay from Lunds universitet/Centrum för analys och syntes

   Author : Andrea Ölander; [2022]
   Keywords : SPPS; Green chemistry; Peptide Synthesis; Organic chemistry; Organisk kemi; Chemistry;

   Abstract : The preferred method for synthesising therapeutic peptides today is by Solid-Phase Peptide Synthesis (SPPS). SPPS is a wasteful process, where the main component of the waste is hazardous solvents, i.e., N,N-dimethylformamide (DMF), N-methylpyrrolidone (NMP) or dichloromethane (DCM). READ MORE

3. 2. 2-Hydroxypyridine-Ligated Pd-complexes as pre-catalysts in Hydrogen Borrowing Chemistry α -Alkylation of Ketones Using Alcohols

   University essay from Lunds universitet/Kemiska institutionen

   Author : Ayesha Kanwal; [2017]
   Keywords : Hydrogen Borrowing in activation of alcohols; Palladium in Catalysis; hydrogenation and dehydrogenation reactions; hydrogen borrowing concept for hydrogenation and dehydrogenation reactions; 2-hydroxyquinoline Ligand; 2-hydroxy pyridine ligands; inorganic chemistry; oorganisk kemi; Chemistry;

   Abstract : An efficient method for selective alpha-alkylation of ketones with alcohols was developed using 2-hydroxypyridine-based ligands coordinated by palladium as pre-catalysts. The reactions were performed without additional additives under mild reaction conditions. The method is environmentally friendly to build C-C bond as water is the only byproduct. READ MORE