Essays about: "receptor mediated uptake"

Found 3 essays containing the words receptor mediated uptake.

  1. 1. Evaluation of mechanisms for accessing intracellular targets for protein-based drugs

    University essay from Uppsala universitet/Avdelningen för farmaceutisk biokemi

    Author : Sonav Jindi Elias; [2021]
    Keywords : intracellular target; neuronal uptake; biological drug; receptor mediated uptake; cell-penetrating peptides;

    Abstract : Over the years, biological drugs have evolved and have made breakthroughs in diseases associated with extracellular proteins. However, intracellular proteins that cause disease progression are still largely inaccessible. READ MORE

  3. 2. A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT

    University essay from SLU/Dept. of Clinical Sciences

    Author : Susanne Andréasson; [2014]
    Keywords : Exendin-4; GLP-1R; pig; beta cell imaging; beta cell mass; Exendin-4; gris; betacellsmassan; PET-CT;

    Abstract : Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. READ MORE

  4. 3. Proliferativ enteropati hos gris : patogenes och patologiska förändringar

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Peter Svanström; [2011]
    Keywords : Proliferativ; Enteropati; Lawsonia; Hemorragisk; Regional; Nekrotisk; Patogenes;

    Abstract : Proliferative enteropathy is a group of disease conditions in pigs where the disease may vary from subclinical to critical with bloody loose feces. The etiological agent is the obligate intracellular bacteria Lawsonia intracellularis. L. intracellularis infects enterocytes from jejunum to colon. READ MORE