Essays about: "recombineering"

Found 3 essays containing the word recombineering.

  1. 1. Potential Application of Multiplex Automated Genome Engineering (MAGE) and One-Step Curing Plasmid System for Environmental Cambodian Enterobacterial Isolates

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Olivia Alexandra; [2021]
    Keywords : Antimicrobial resistance; plasmid curing; environmental isolates; recombineering; enterobacteria;

    Abstract : Antimicrobial resistance (AMR) is concerning because it limits antimicrobial drug treatment options. AMR occurs by the overuse and misuse of antimicrobial drugs. In environmental settings, AMR can disseminate from places of high use, which leads to increased exposure to humans and animals. READ MORE

  3. 2. Antibiotic combination therapies against carbapenamse producing Klebsiella pneumoniae

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Thomas Söderhäll; [2021]
    Keywords : Klebsiella pneumoniae; carbapenem resistance; carbapenemase; combination therapy; meropenem; colistin; avibactam; constucts; porins;

    Abstract : The treatment options for multidrug resistant bacteria are dwindling and it is an important issue of research in medicine to solve. One of the more problematic bacterial species is Klebsiella pneumoniae, it can cause infections with high morbidity that are difficult to treat. READ MORE

  4. 3. HisA mutants with minor structural differences display major functional deviations

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Struktur- och molekylärbiologi

    Author : András Erdélyi; [2016]
    Keywords : ;

    Abstract : Even though enzymes tend to specialize on one reaction during evolution, enzyme promiscuity is an abundant phenomenon. The subject of this thesis is the Salmonella enterica N’-[(5’-phosphosoribosyl)-formimino]-5-aminoimidazole-4 carboxamide-ribonucleotide (ProFAR) isomerase (SeHisA), a (βα)8-barrel enzyme from the histidine biosynthesis that catalyzes one reaction on one substrate in one organism. READ MORE